Imperial College London
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DrFelicityFitzgerald

Faculty of Medicine, Department of Infectious Disease

Senior Clinical Research Fellow
 
 
 
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Contact

 

f.fitzgerald

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Fitzgerald:2016:10.3201/eid2210.160579,
author = {Fitzgerald, F and Naveed, A and Wing, K and Gbessay, M and Ross, JCG and Checchi, F and Youkee, D and Jalloh, MB and Baion, D and Mustapha, A and Jah, H and Lako, S and Oza, S and Boufkhed, S and Feury, R and Bielicki, JA and Gibb, DM and Klein, N and Sahr, F and Yeung, S},
doi = {10.3201/eid2210.160579},
journal = {Emerging Infectious Diseases},
pages = {1769--1777},
title = {Ebola virus disease in children, Sierra Leone, 2014-2015.},
url = {http://dx.doi.org/10.3201/eid2210.160579},
volume = {22},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Little is known about potentially modifiable factors in Ebola virus disease in children. We undertook a retrospective cohort study of children <13 years old admitted to 11 Ebola holding units in the Western Area, Sierra Leone, during 2014-2015 to identify factors affecting outcome. Primary outcome was death or discharge after transfer to Ebola treatment centers. All 309 Ebola virus-positive children 2 days-12 years old were included; outcomes were available for 282 (91%). Case-fatality was 57%, and 55% of deaths occurred in Ebola holding units. Blood test results showed hypoglycemia and hepatic/renal dysfunction. Death occurred swiftly (median 3 days after admission) and was associated with younger age and diarrhea. Despite triangulation of information from multiple sources, data availability was limited, and we identified no modifiable factors substantially affecting death. In future Ebola virus disease epidemics, robust, rapid data collection is vital to determine effectiveness of interventions for children.
AU  - Fitzgerald,F
AU  - Naveed,A
AU  - Wing,K
AU  - Gbessay,M
AU  - Ross,JCG
AU  - Checchi,F
AU  - Youkee,D
AU  - Jalloh,MB
AU  - Baion,D
AU  - Mustapha,A
AU  - Jah,H
AU  - Lako,S
AU  - Oza,S
AU  - Boufkhed,S
AU  - Feury,R
AU  - Bielicki,JA
AU  - Gibb,DM
AU  - Klein,N
AU  - Sahr,F
AU  - Yeung,S
DO  - 10.3201/eid2210.160579
EP  - 1777
PY  - 2016///
SN  - 1080-6040
SP  - 1769
TI  - Ebola virus disease in children, Sierra Leone, 2014-2015.
T2  - Emerging Infectious Diseases
UR  - http://dx.doi.org/10.3201/eid2210.160579
UR  - https://www.ncbi.nlm.nih.gov/pubmed/27649367
UR  - https://wwwnc.cdc.gov/eid/article/22/10/16-0579_article
UR  - http://hdl.handle.net/10044/1/100176
VL  - 22
ER  -
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