Imperial College London
Alternate

DrFiratGuder

Faculty of Engineering, Department of Bioengineering

Reader in Intelligent Interfaces
 
 
 
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Contact

 

f.guder

 
 
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Location

 

Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Maier:2019:10.1021/acssensors.9b01403,
author = {Maier, D and Laubender, E and Basavanna, A and Schumann, S and Guder, F and Urban, G and Dincer, C},
doi = {10.1021/acssensors.9b01403},
journal = {ACS Sensors},
pages = {2945--2951},
title = {Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath},
url = {http://dx.doi.org/10.1021/acssensors.9b01403},
volume = {4},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Exhaled breath contains a large amount of biochemical and physiological information concerning one’s health and provides an alternative route to noninvasive medical diagnosis of diseases. In the case of lung diseases, hydrogen peroxide (H2O2) is an important biomarker associated with asthma, chronic obstructive pulmonary disease, and lung cancer and can be detected in exhaled breath. The current method of breath analysis involves condensation of exhaled breath, is not continuous or real time, and requires two separate and bulky devices, complicating the periodic or long-term monitoring of a patient. We report the first disposable paper-based electrochemical wearable sensor that can monitor exhaled H2O2 in artificial breath calibration-free and continuously, in real time, and can be integrated into a commercial respiratory mask for on-site testing of exhaled breath. To improve precision for sensing H2O2, we perform differential electrochemical measurement by amperometry in which screen-printed Prussian Blue-mediated and nonmediated carbon electrodes are used for differential analysis. We were able to measure H2O2 in simulated breath in a concentration-dependent manner in real time, confirming its functionality. This proposed system is versatile, and by modifying the chemistry of the sensing electrodes, our method of differential sensing can be extended to continuous monitoring of other analytes in exhaled breath.
AU  - Maier,D
AU  - Laubender,E
AU  - Basavanna,A
AU  - Schumann,S
AU  - Guder,F
AU  - Urban,G
AU  - Dincer,C
DO  - 10.1021/acssensors.9b01403
EP  - 2951
PY  - 2019///
SN  - 2379-3694
SP  - 2945
TI  - Toward Continuous Monitoring of Breath Biochemistry: A Paper-Based Wearable Sensor for Real-Time Hydrogen Peroxide Measurement in Simulated Breath
T2  - ACS Sensors
UR  - http://dx.doi.org/10.1021/acssensors.9b01403
UR  - http://hdl.handle.net/10044/1/74542
VL  - 4
ER  -
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