Imperial College London
Alternate

Dr Francine Heatley

Faculty of Medicine, Department of Surgery & Cancer

Clinical Trials Manager
 
 
 
//

Contact

 

+44 (0)20 3311 7371f.heatley Website

 
 
//

Location

 

3E4East WingCharing Cross Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Epstein:2018:10.1002/bjs5.56,
author = {Epstein, D and Gohel, MS and Heatley, FM and Davies, A},
doi = {10.1002/bjs5.56},
journal = {BJS Open},
pages = {203--212},
title = {Cost-effectiveness of treatments for superficial venous refluxin patients with chronic venous ulceration.},
url = {http://dx.doi.org/10.1002/bjs5.56},
volume = {2},
year = {2018}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundVenous leg ulcers impair quality of life significantly, with substantial costs to health services. The aim of this study was to estimate the costeffectiveness of interventional procedures alongside compression therapy versus compression therapy alone for the treatment of chronic venous leg ulceration.MethodsA Markov decision analytical model was developed. The main outcome measures were qualityadjusted lifeyears (QALYs) and lifetime costs per patient, from the perspective of the UK National Health Service at 2015 prices. Resource use included the initial procedures, compression therapy, primary care and outpatient consultations. The interventional procedures included superficial venous surgery, endothermal ablation and ultrasoundguided foam sclerotherapy (UGFS). The study population was patients with a chronic venous ulcer who were eligible for either compression therapy or an interventional procedure. Data were obtained from systematic review and metaanalysis of RCTs.ResultsSurgery gained 0·112 (95 per cent c.i. −0·011 to 0·213) QALYs compared with compression therapy alone, with a difference in lifetime costs of €−1330 (−3570 to 1262). Given the expected savings in community care, the procedure would pay for itself within 4 years. There was insufficient evidence regarding endothermal ablation and UGFS to draw conclusions.DiscussionThis modelling study found surgery to be more effective and less costly than compression therapy alone. Further RCT evidence is required for both endothermal ablation and UGFS.
AU  - Epstein,D
AU  - Gohel,MS
AU  - Heatley,FM
AU  - Davies,A
DO  - 10.1002/bjs5.56
EP  - 212
PY  - 2018///
SN  - 2474-9842
SP  - 203
TI  - Cost-effectiveness of treatments for superficial venous refluxin patients with chronic venous ulceration.
T2  - BJS Open
UR  - http://dx.doi.org/10.1002/bjs5.56
UR  - http://hdl.handle.net/10044/1/59341
VL  - 2
ER  -
Download