Overview
Dr Ng's research spans the entire research spectrum, from laboratory cardiac optical mapping experiments on explanted hearts, through to first-in-human invasive studies in patients. He has also developed a recent interest in applying AI methods and novel signal processing tools for diagnosis, tailoring treatments and risk stratification.
Atrial and ventricular fibrillation
Figure 1: The cardiac electrophenotype spectrum. Reproduced from Handa et al, Cardiovasc Res 2021 under CC-BY license. https://doi.org/10.1093/cvr/cvaa141
Research Student Supervision
Boardman,D, Effect of gap junction modulation on oxidative stress in remote non-ischaemic myocardium
Chang,ETY, MRes: Carbenoxolone affects connexin43 expression in HL-1 cardiomyocytes and ischaemic rat ventricular tissue
Cooper,SA, BSc: Heterogeneity of fibrosis in the infarct border zone correlates to arrhythmogenicity post-myocardial infarction
Debney,MT, PhD: Enhancing Gap Junction Coupling in Reperfused Myocardium
Ferraro,E, PhD: Ursodeoxycholic acid: mechanism of antiarrhythmic and cardioprotective action in the chronic post-myocardial infarction heart
Handa,B, PhD: Fibrosis and gap junction coupling as determinants of myocardial fibrillation dynamics
Jabbour,R, PhD: Mechanisms of arrhythmia generation from implanted stem cell-derived cardiomyocytes in infarcted hearts
Jenkins,C, MRes: The electrophysiological phenotype in chronic inflammation in a model of systemic lupus erythematosus
Kalindjian,J, BSc: Assessment of infarct border zone morphology following modification by pharmacological gap junction modulators
Leong,KMW, PhD: Multiscale electrophysiological phenotyping to define the clinical signatures of risk in the inherited cardiac conditions
Owusu-Agyei,AA, BSc: The Gap Junction Modulator ZP1210 Prevents Ischaemia-Induced Connexin43 Dephosphorylation
Patel,K, PhD: Subclinical electrophysiological remodelling in the metabolic syndromes
Roney,C, MRes: The role of connexins and gap junctional coupling in conduction velocity restitution and short-term cardiac memory
Roney,CH, PhD: Mathematical techniques for assessing cardiac wavefront dynamics