Imperial College London

DrFelipeOrihuela-Espina

Faculty of MedicineDepartment of Surgery & Cancer

Honorary Lecturer
 
 
 
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Publications

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119 results found

Moran AL, Ramirez-Fernandez C, Meza-Kubo V, Orihuela-Espina F, Garcia-Canseco E, Grimaldo AI, Sucar Eet al., 2015, On the Effect of Previous Technological Experience on the Usability of a Virtual Rehabilitation Tool for the Physical Activation and Cognitive Stimulation of Elders, JOURNAL OF MEDICAL SYSTEMS, Vol: 39, ISSN: 0148-5598

Journal article

Rivas JJ, Orihuela-Espina F, Sucar LE, Palafox L, Hernandez-Franco J, Bianchi-Berthouze Net al., 2015, Detecting affective states in virtual rehabilitation, 9th International Conference on Pervasive Computing Technologies for Healthcare, Publisher: IEEE, Pages: 287-292, ISSN: 2153-1633

Conference paper

Shetty K, Leff DR, Orihuela-Espina F, Selvadurai S, Chaudery M, Athanasiou T, Yang GZ, Darzi Aet al., 2015, Looks can be deceiving: is there value in cognitive assessment of complex surgical skills?, Annual Meeting of the Society-of-Academic-and-Research-Surgery (SARS(, Publisher: WILEY-BLACKWELL, Pages: 43-43, ISSN: 0007-1323

Conference paper

Rivas JJ, Heyer P, Orihuela-Espina F, Enrique Sucar Let al., 2015, Towards incorporating affective computing to virtual rehabilitation: surrogating attributed attention from posture for boosting therapy adaptation, 10th International Symposium on Medical Information Processing and Analysis, Publisher: SPIE, ISSN: 0277-786X

Conference paper

Orihuela-Espina F, Fernandez del Castillo I, Palafox L, Pasaye E, Sanchez-Villavicencio I, Leder R, Hernandez Franco J, Enrique Sucar Let al., 2015, Neural reorganization accompanying upper limb motor rehabilitation from stroke with virtual reality-based gesture therapy, Topics in Stroke Rehabilitation, Vol: 20, Pages: 197-209, ISSN: 1074-9357

Journal article

Davis J, Sucar LE, Orihuela-Espina F, 2015, Treatment of disease: The role of knowledge representation for treatment selection, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol: 9521 LNCS, Pages: 235-241, ISSN: 0302-9743

Journal article

Sucar LE, Ávila-Sansores SM, Orihuela-Espina F, 2015, User modelling for patient tailored virtual rehabilitation, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol: 9521 LNCS, Pages: 259-278, ISSN: 0302-9743

Intelligent rehabilitation is a novel paradigm in motor rehabilitation empowering assistive technology with artificial intelligence (AI). Central to this paradigm is adaptation, the capacity of the assistive technology to dynamically accommodate to the therapy evolving demands. This chapter overviews several existing AI solutions to implement a decision making model to provide rehabilitation tools with adaptation capabilities, and provides details of a powerful approach capable of exploiting prior knowledge for a quick start and posterior knowledge to guarantee up-to-dated informed decisions. In this solution, a Markov decision process formulates an initial policy optimal within prior knowledge; a policy which is later on allow to evolve on incoming evidence to fit new requirements. This solution ensures short training periods and exhibits convergence with therapists’ criteria. In consequence, intelligent adaptation to dynamic circumstances of the patient and therapy plan is demonstrated a feasible endeavour within a real practical timeline. This might endow assistive technology with the necessary competence to be taken home and/or reduce expert surpervision.

Journal article

Lucas PJF, Orihuela-Espina F, 2015, Representing knowledge for clinical diagnostic reasoning, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol: 9521 LNCS, Pages: 35-45, ISSN: 0302-9743

Journal article

Moran AL, Orihuela-Espina F, Meza-Kubo V, Grimaldo AI, Ramirez-Fernandez C, Garcia-Canseco E, Oropeza-Salas JM, Sucar LEet al., 2015, Out of context serious games: Transversal reutilization of games across healthcare domains, COMPUTER SYSTEMS SCIENCE AND ENGINEERING, Vol: 30, Pages: 43-55, ISSN: 0267-6192

Journal article

Heyer P, Rivas JJ, Enrique Sucar L, Orihuela-Espina Fet al., 2015, Improving classification of posture based attributed attention assessed by ranked crowd-raters, 9th International Conference on Pervasive Computing Technologies for Healthcare (PervasiveHealth), Publisher: IEEE, Pages: 277-279, ISSN: 2153-1633

Conference paper

Garcia-Martinez S, Orihuela-Espina F, Enrique Sucar L, Moran AL, Hernandez-Franco Jet al., 2015, A Design Framework for Arcade-Type Games for the Upper-Limb Rehabilitation, International Conference on Virtual Rehabilitation Proceedings (ICVR), Publisher: IEEE, Pages: 235-242

Conference paper

Borrego G, Moran AL, LaFlor A, Meza V, Garcia-Canseco E, Orihuela-Espina F, Enrique Sucar Let al., 2015, Pilot Evaluation of a Collaborative Game for Motor Tele-Rehabilitation and Cognitive Stimulation of the Elderly, 7th International Work-Conference on Ambient Assisted Living (IWAAL), Publisher: SPRINGER INT PUBLISHING AG, Pages: 42-48, ISSN: 0302-9743

Conference paper

Ramirez-Fernandez C, Garcia-Canseco E, Moran AL, Orihuela-Espina Fet al., 2015, Design Principles for Hapto-Virtual Rehabilitation Environments: Effects on Effectiveness of Fine Motor Hand Therapy, 2nd International Workshop on ICTs for Improving Patients Rehabilitation Research Techniques (REHAB), Publisher: SPRINGER-VERLAG BERLIN, Pages: 270-284, ISSN: 1865-0929

Conference paper

Paggetti G, Leff DR, Orihuela-Espina F, Mylonas G, Darzi A, Yang G-Z, Menegaz Get al., 2014, The role of the posterior parietal cortex in stereopsis and hand-eye coordination during motor task behaviours, Cognitive Processing, Vol: 16, Pages: 177-190, ISSN: 1612-4790

Journal article

Ramírez-Fernández C, Morán AL, García-Canseco E, Orihuela-Espina Fet al., 2014, Design factors of virtual environments for upper limb motor rehabilitation of stroke patients, Pages: 22-25

Stroke survivors are often left with motor disabilities. Virtual environments for motor therapy are an emerging stra-Tegy to motivate, entertain or engage the rehabilitation patient to the therapy after stroke. The design of these specialized virtual environments requires to meet the needs of patients and therapists, which is not a simple task. To support the design of these applications a number of re- commendations for the developers have been proposed in literature. Here, a taxonomy is proposed to classify the identified principles, criteria, implications, usability factors or guidelines on which the recommendations are based. The taxonomy identifies key factors in the design of virtual en- vironments for upper limb motor therapy. The taxonomy is organized into three categories corresponding to different stages of the therapy: configuration of the exercise, assis-Tance during the execution of the exercise and management of therapy results. We believe that agglutinating and or- ganizing design factors into a taxonomy may reduce development times, facilitate communication between developers and clinical counterparts and increase chances of therapeutic validity.

Conference paper

Morán AL, Meza V, Ramírez-fernández C, Grimaldo AI, García-canseco E, Orihuela-espina F, Sucar LEet al., 2014, Revisiting the user experience of a virtual rehabilitation tool for the physical activation and cognitive stimulation of elders, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol: 8868, Pages: 203-210, ISSN: 0302-9743

We report the results of an indirect observation usability and user experience (UX) study on the use of the Gesture Therapy (GT) rehabilitation platform, as a physical activation and cognitive stimulation tool for the elderly. The results from this study complement those of a former self-report study [8]. Elders perceived the system with high usefulness, usability, and UX, as well as generating low anxiety in both studies. Also, the results allowed us to analyze and evaluate the impact of elders’ previous experience on computer use on specific aspects. Interestingly, the significance of the effect of previous computer use experience on perceived anxiety and perceived enjoyment aspects of UX was different in both studies, although there is an important overlap for ease of use factors. These results, although not conclusive yet on the causes for the difference, provides us with further evidence to establish that elders’ previous experience (or not) on computer use affects their user experience on the use of the GT platform.

Journal article

Sanchez-Perez KJ, Herrera-Vega J, Sucar-Succar E, Orilluela-Espina F, Trevino-Palacios CGet al., 2014, Developing a Device for Monitoring O<sub>2</sub> Saturation in Blood, 13th Mexican Symposium on Medical Physics, Publisher: AMER INST PHYSICS, Pages: 201-204, ISSN: 0094-243X

Conference paper

Heyer P, Herrera-Vega J, Vila Rosado D-EN, Enrique Sucar L, Orihuela-Espina Fet al., 2014, Posture Based Detection of Attention in Human Computer Interaction, 6th Pacific-Rim Symposium on Image and Video Technology (PSIVT), Publisher: SPRINGER-VERLAG BERLIN, Pages: 220-229, ISSN: 0302-9743

Conference paper

Enrique Sucar L, Orihuela-Espina F, Luis Velazquez R, Reinkensmeyer DJ, Leder R, Hernandez-Franco Jet al., 2013, Gesture therapy: an upper limb virtual reality-based motor rehabilitation platform, IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol: 22, Pages: 634-643, ISSN: 1558-0210

Journal article

Morán AL, Orihuela-Espina F, Meza-Kubo V, Grimaldo AI, Ramírez-Fernández C, García-Canseco E, Oropeza-Salas JM, Sucar LEet al., 2013, Borrowing a virtual rehabilitation tool for the physical activation and cognitive stimulation of elders, Pages: 95-102, ISSN: 0302-9743

We explore the use of a virtual rehabilitation platform as the interaction means for physical activation and cognitive stimulation of elders. A usability evaluation of actual and projected use of the tool suggests that this could be feasible to perform. Elders perceived the use of the evaluated tool as useful (93.75/100), easy to use (93.75/100) and pleasurable to use (91.66/100) during an actual activation and stimulation session. Previous experience on the use of computers by the participants did not significantly impact on their usability perception for most of the included factors, with the sole exception being the perception of anxiety. This is an encouraging result to reuse and adapt technologies from "close" domains (e.g., virtual rehabilitation). In addition, this can reduce development times and cost, and facilitate knowledge transfer into the domain of physical activation and cognitive stimulation of elders. © 2013 Springer International Publishing.

Conference paper

Orihuela-Espina F, Alvarez-Cardenas P, Palafox L, Sanchez-Villavicencio I, Moran AL, Hernandez-Franco J, Enrique Sucar Let al., 2013, New developments in the gesture therapy platform past, present and future of our research, Neurotechnix 2013, Publisher: SCITEPRESS, Pages: 106-113

Gesture Therapy (GT) is a virtual rehabilitation tool for the upper arm that has been in the making since 2008, and by now has successfully demonstrated therapeutic validity in two small clinical trials for stroke survivors. During this time, our group has published a number of contributions regarding different aspects of this platform ranging from hardware controllers to artificial intelligence algorithms guiding different aspects of the serious games behaviour, and clinical trial data from observable improvements in dexterity to changes in functional neuroreorganization. As we continue our research efforts in virtual rehabilitation and realising this knowledge in the GT platform, this paper presents an overview of the latest developments as well as a roadmap for future research.

Conference paper

Hernandez-Leal P, Rios-Flores A, Ávila-Rios S, Reyes-Terán G, Gonzalez JA, Fiedler-Cameras L, Orihuela-Espina F, Morales EF, Sucar LEet al., 2013, Discovering human immunodeficiency virus mutational pathways using temporal Bayesian networks, Artificial Intelligence in Medicine, Vol: 57, Pages: 185-195, ISSN: 0933-3657

Objective: The human immunodeficiency virus (HIV)is one ofthe fastest evolving organisms in the planet.Its remarkable variation capability makes HIV able to escape from multiple evolutionary forces naturallyor artificially acting on it, through the development and selection of adaptive mutations. Although mostdrug resistance mutations have been well identified, the dynamics and temporal patterns of appearanceof these mutations can still be further explored. The use of models to predict mutational pathways as wellas temporal patterns of appearance of adaptive mutations could greatly benefit clinical management ofindividuals under antiretroviral therapy.Methods and material: We apply a temporal nodes Bayesian network (TNBN) modelto data extracted fromthe Stanford HIVdrug resistance database in order to explore the probabilistic relationships between drugresistance mutations and antiretroviral drugs unveiling possible mutational pathways and establishingtheir probabilistic-temporal sequence of appearance.Results: In a first experiment, we compared the TNBN approach with other models such as static Bayesiannetworks, dynamic Bayesian networks and association rules. TNBN achieved a 64.2% sparser structureover the static network. In a second experiment, the TNBN model was applied to a dataset associatingantiretroviral drugs with mutations developed under different antiretroviral regimes. The learned modelscaptured previously described mutational pathways and associations between antiretroviral drugs anddrug resistance mutations. Predictive accuracy reached 90.5%.Conclusion: Our results suggest possible applications of TNBN for studying drug-mutation andmutation–mutation networks in the context of antiretroviral therapy, with direct impact on the clinicalmanagement of patients under antiretroviral therapy. This opens new horizons for predicting HIV mutationalpathways in immune selection with relevance for antiretroviral drug development and therapyplan.

Journal article

Clark J, Orihuela-Espina F, Sodergren M, James DRC, Karimyan V, Teare J, Darzi A, Yang G-Zet al., 2013, A quantitative scale to define endoscopic torque control during natural orifice surgery, MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES, Vol: 22, Pages: 17-25, ISSN: 1364-5706

Journal article

Ávila-Sansores S, Orihuela-Espina F, Enrique-Sucar L, 2013, Patient tailored virtual rehabilitation, Biosystems and Biorobotics, Pages: 879-883

Virtual rehabilitation should be adaptable to the patient need and progress. To do so, patient in-game performace and ability are monitored to maintain an adequate level of challenge. A novel adaptation strategy is proposed by which patient control and speed are dynamically interrogated to adjust the game difficulty. The strategy is based on a Markov decision process seeding a therapist-guided reinforcement learning algorithm. The optimal learning scheme for the algorithm is established (α = 0.5). Convergence to an optimal therapeutic plan is demonstrated for patients with non-deterministic behaviour. The proposed adaptation algorithm can enhance existing virtual reality-based motor rehabilitation platforms by tailoring the games response to the patient changing needs.

Book chapter

Hernandez-Leal P, Orihuela-Espina F, Sucar LE, Morales EFet al., 2012, Hybrid binary-chain multi-label classifiers, Pages: 139-146

In multi-label classification the goal is to assign an instance to a set of different classes. Several approaches have been proposed to deal with multi-label classification problems, ranging from considering each class independently from the other (binary relevance methods) to considering all the possible combinations of values of the original classes into a single compound class (power-set approach). In between, other methods have been proposed to consider dependencies among classes whilst trying to keep computational complexity of the method low. In this paper, instead of finding probabilistic dependencies among classes, we focused on finding independencies among classes using a simple correlation approach. We first build a correlation matrix among classes and use it to build chain classifiers among correlated sub-sets of classes while learning independent classifiers for uncorrelated classes. It is experimentally shown that this simple hybrid approach exhibits very competitive predictive performance among state-of-the-art multi-label classifiers with lower time complexity.

Conference paper

Kwok K-W, Sun L-W, Mylonas GP, James DRC, Orihuela-Espina F, Yang G-Zet al., 2012, Collaborative Gaze Channelling for Improved Cooperation During Robotic Assisted Surgery, ANNALS OF BIOMEDICAL ENGINEERING, Vol: 40, Pages: 2156-2167, ISSN: 0090-6964

Journal article

James DR, Leff DR, Orihuela-Espina F, Kwok KW, Mylonas GP, Kwok KW, Athanasiou T, Darzi A, Yang GZet al., 2012, Enhanced frontoparietal network architectures following "gaze-contingent" versus "free-hand" motor learning., Neuroimage

Journal article

Mylonas GP, Kwok K-W, James DRC, Leff D, Orihuela-Espina F, Darzi A, Yang G-Zet al., 2012, Gaze-Contingent Motor Channelling, haptic constraints and associated cognitive demand for robotic MIS, MEDICAL IMAGE ANALYSIS, Vol: 16, Pages: 612-631, ISSN: 1361-8415

Journal article

Yongue G, Leff DR, James DRC, Vlaev I, Orihuela-Espina F, Seymour B, Dolan R, Yang GZ, Darzi AWet al., 2012, Expertise related disparity in prefrontal cortical excitation associated with intra-operative decision making, Annual Meeting of the Society-of-Academic-and-Research-Surgery, Publisher: WILEY-BLACKWELL, Pages: 39-39, ISSN: 0007-1323

Conference paper

Karimyan V, Orihuela-Espina F, Leff DR, Clark J, Sodergren M, Darzi A, Yang G-Zet al., 2012, Spatial awareness in Natural Orifice Transluminal Endoscopic Surgery (NOTES) navigation, INTERNATIONAL JOURNAL OF SURGERY, Vol: 10, Pages: 80-86, ISSN: 1743-9191

Journal article

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