DrFionaWatt

Faculty of Medicine, Department of Immunology and Inflammation

Reader in Rheumatology

Contact

Location

Commonwealth BuildingHammersmith Campus

Summary

I am a Clinical Reader, Honorary Consultant Rheumatologist and a UKRI Future Leaders Fellow. My clinical and research interest is in the commonest form of arthritis, osteoarthritis. My particular focus is in the clinical and biological factors which predict outcome in high risk groups and the development of new tests and treatments for the condition.

Selected Publications

Journal Articles

Williams JAE, Chester-Jones M, Lowe CM, et al.Williams JAE, Chester-Jones M, Lowe CM, Goff M, Francis A, Brewer G, Marian I, Morris SL, Warwick D, Eldridge L, Julier P, Gulati M, Barker KL, Barber VS, Black J, Woollacott S, Mackworth-Young C, Glover V, Lamb SE, Vincent TL, Vincent K, Dutton SJ, Watt FE close, 2022, Hormone replacement therapy (conjugated oestrogens plus bazedoxifene) for post-menopausal women with symptomatic hand osteoarthritis: primary report from the HOPE-e randomised, placebo-controlled, feasibility study, The Lancet Rheumatology, Vol:4, ISSN:2665-9913, Pages:E725-E737

Watt F, 2022, Treating post-menopausal women with symptomatic hand osteoarthritis with hormone replacement therapy (conjugated estrogens and bazedoxifene): primary report from the HOPE-e randomised placebo-controlled feasibility study, The Lancet Rheumatology, ISSN:2665-9913

Open Access Link

Paskins Z, Farmer CE, Manning F, et al.Paskins Z, Farmer CE, Manning F, Andersson DA, Barlow T, Bishop FL, Brown CA, Clark A, Clark EM, Dulake D, Gulati M, Le Maitre CL, Jones RK, Loughlin J, Mason DJ, McCarron M, Millar NL, Pandit H, Peat G, Richardson SM, Salt EJ, Taylor EJ, Troeberg L, Wilcox RK, Wise E, Wilkinson C, Watt FE close, 2022, Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method, The Lancet Rheumatology, Vol:4, ISSN:2665-9913, Pages:e635-e645

Garriga C, Goff M, Paterson E, et al.Garriga C, Goff M, Paterson E, Hrusecka R, Hamid B, Alderson J, Leyland K, Honeyfield L, Greenshields L, Satchithananda K, Lim A, Arden NK, Judge A, Williams A, Vincent TL, Watt FE close, 2021, Clinical and molecular associations with outcomes at two years after acute knee injury: a longitudinal study in the Knee Injury Cohort at the Kennedy (KICK), The Lancet Rheumatology, Vol:3, ISSN:2665-9913, Pages:e648-e658

Watt FE, Wise EM, 2021, Osteoarthritis and associated comorbidities: new answers and more questions, Rheumatology, Vol:60, ISSN:1462-0324, Pages:3966-3968

Marian IR, Goff M, Williams JAE, et al.Marian IR, Goff M, Williams JAE, Gulati M, Chester-Jones M, Francis A, Watson M, Vincent TL, Woollacott S, Mackworth-Young C, Glover V, Furniss D, Gardiner M, Lamb SE, Vincent K, Barber VS, Black J, Dutton SJ, Watt FE close, 2021, Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial, Pilot and Feasibility Studies, Vol:7, ISSN:2055-5784, Pages:1-14

Mason D, Englund M, Watt FE, 2021, Prevention of posttraumatic osteoarthritis at the time of injury: Where are we now, and where are we going?, Journal of Orthopaedic Research, Vol:39, ISSN:0736-0266, Pages:1152-1163

Watt FE, 2021, Posttraumatic osteoarthritis: what have we learned to advance osteoarthritis?, Current Opinion in Rheumatology, Vol:33, ISSN:1040-8711, Pages:74-83

Watt FE, Blauwet MB, Fakhoury A, et al.Watt FE, Blauwet MB, Fakhoury A, Jacobs H, Smulders R, Lane NE close, 2019, Tropomyosin-related kinase A (TrkA) inhibition for the treatment of painful knee osteoarthritis: results from a randomized controlled phase 2a trial, Osteoarthritis and Cartilage, Vol:27, ISSN:1063-4584, Pages:1590-1598

Watt FE, Corp N, Kingsbury SR, et al.Watt FE, Corp N, Kingsbury SR, Frobell R, Englund M, Felson DT, Levesque M, Majumdar S, Wilson C, Beard DJ, Lohmander LS, Kraus VB, Roemer F, Conaghan PG, Mason DJ, Arthritis Research UK Osteoarthritis and Crystal Disease Clinical Study Group Expert Working Group close, 2019, Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury, Osteoarthritis and Cartilage, Vol:27, ISSN:1063-4584, Pages:23-33

Kingsbury SR, Tharmanathan P, Keding A, et al.Kingsbury SR, Tharmanathan P, Keding A, Ronaldson SJ, Grainger A, Wakefield RJ, Arundel C, Birrell F, Doherty M, Vincent T, Watt FE, Dziedzic K, O'Neill TW, Arden NK, Scott DL, Dickson J, Garrood T, Green M, Menon A, Sheeran T, Torgerson D, Conaghan PG close, 2018, Hydroxychloroquine Effectiveness in Reducing Symptoms of Hand Osteoarthritis A Randomized Trial, Annals of Internal Medicine, Vol:168, ISSN:0003-4819, Pages:385-+

Watt FE, 2018, Osteoarthritis biomarkers: year in review, Osteoarthritis and Cartilage, Vol:26, ISSN:1063-4584, Pages:312-318

Watt FE, Paterson E, Freidin A, et al.Watt FE, Paterson E, Freidin A, Kenny M, Judge A, Saklatvala J, Williams A, Vincent TL close, 2016, Acute molecular changes in synovial fluid following human knee injury: association with early clinical outcomes, Arthritis & Rheumatology, Vol:68, ISSN:2326-5205, Pages:2129-2140

Kingsbury SR, Corp N, Watt FE, et al.Kingsbury SR, Corp N, Watt FE, Felson DT, O'Neill TW, Holt CA, Jones RK, Conaghan PG, Arden NK close, 2016, Harmonising data collection from osteoarthritis studies to enable stratification: recommendations on core data collection from an Arthritis Research UK clinical studies group, Rheumatology, Vol:55, ISSN:1462-0324, Pages:1394-1402

Watt FE, 2016, Hand osteoarthritis, menopause and menopausal hormone therapy, Maturitas, Vol:83, ISSN:0378-5122, Pages:13-18

Watt FE, Kennedy DL, Carlisle KE, et al.Watt FE, Kennedy DL, Carlisle KE, Freidin AJ, Szydlo RM, Honeyfield L, Satchithananda K, Vincent TL close, 2014, Night-time immobilization of the distal interphalangeal joint reduces pain and extension deformity in hand osteoarthritis, Rheumatology, Vol:53, ISSN:1462-0332, Pages:1142-1149

Watt FE, Ismail HM, Didangelos A, et al.Watt FE, Ismail HM, Didangelos A, Peirce M, Vincent TL, Wait R, Saklatvala J close, 2013, Src and Fibroblast Growth Factor 2 Independently Regulate Signaling and Gene Expression Induced by Experimental Injury to Intact Articular Cartilage, Arthritis and Rheumatism, Vol:65, ISSN:0004-3591, Pages:397-407

Alexander S, Watt F, Sawaji Y, et al.Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J close, 2007, Activin a is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappa B, Arthritis and Rheumatism, Vol:56, ISSN:0004-3591, Pages:3715-3725

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