Imperial College London
Alternate

Professor Fang Xie

Faculty of Engineering, Department of Materials

Professor of Functional Materials
 
 
 
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Contact

 

+44 (0)20 7594 9693f.xie Website

 
 
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Location

 

1.03Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Xie:2020:10.1149/ma2020-01272002mtgabs,
author = {Xie, F},
doi = {10.1149/ma2020-01272002mtgabs},
journal = {ECS Meeting Abstracts},
pages = {2002--2002},
title = {(Invited) Nanoscale Engineering of Plasmonic Materials for Biosensing and Bioimaging},
url = {http://dx.doi.org/10.1149/ma2020-01272002mtgabs},
volume = {MA2020-01},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:p>  Early diagnosis plays an increasingly significant role in current clinical drive. Detection, identification, and quantification of low abundance biomarker proteins form a promising basis for early clinical diagnosis and offer a range of important medical benefits. Amplification of light from NIR fluorophores by coupling to metal nanostructures, i.e. Metal Induced Fluorescence Enhancement (MIFE), represents a promising strategy for dramatically improving the detection and quantification of low abundance biomarker proteins, and potentially increase already sensitive fluorescence-based detection by up to three orders of magnitude. The amplification of the fluorescence system is based on interaction of the excited fluorophores with the surface plasmon resonance in metallic nanostructures. The enhanced fluorescence intensity due to the existence of metal nanostructures makes it possible to detect much lower levers of biomarkers tagged with fluorescence molecules either in sensing format or for tissue imaging. The first part of my talk will focus on some recent developments of plasmonic metal nanostructures by both “top-down” and “bottom up” methods. I will then discuss the prepared plasmonic nanostructures in the applications of biosensing and bioimaging, with the emphasis on plasmonic enhancement towards NIR I and NIR II regions.    </jats:p>
AU  - Xie,F
DO  - 10.1149/ma2020-01272002mtgabs
EP  - 2002
PY  - 2020///
SP  - 2002
TI  - (Invited) Nanoscale Engineering of Plasmonic Materials for Biosensing and Bioimaging
T2  - ECS Meeting Abstracts
UR  - http://dx.doi.org/10.1149/ma2020-01272002mtgabs
VL  - MA2020-01
ER  -
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