Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Research Fellow







ICTEM buildingHammersmith Campus






BibTex format

author = {Zucchelli, E and Majid, QA and Foldes, G},
doi = {10.1530/VB-19-0026},
journal = {Vascular Biology},
pages = {H135--H143},
title = {New artery of knowledge: 3D models of angiogenesis},
url = {},
volume = {1},
year = {2019}

RIS format (EndNote, RefMan)

AB - Angiogenesis and vasculogenesis are complex processes by which new blood vessels are formed and expanded. They play a pivotal role not only in physiological development and growth and tissue and organ repair, but also in a range of pathological conditions, from tumour formation to chronic inflammation and atherosclerosis. Understanding the multistep cell-differentiation programmes and identifying the key molecular players of physiological angiogenesis/vasculogenesis are critical to tackle pathological mechanisms. While many questions are yet to be answered, increasingly sophisticated in vitro, in vivo and ex vivo models of angiogenesis/vasculogenesis, together with cutting-edge imaging techniques, allowed for recent major advances in the field. This review aims to summarise the three-dimensional models available to study vascular network formation and to discuss advantages and limitations of the current systems.
AU - Zucchelli,E
AU - Majid,QA
AU - Foldes,G
DO - 10.1530/VB-19-0026
EP - 143
PY - 2019///
SN - 2516-5658
SP - 135
TI - New artery of knowledge: 3D models of angiogenesis
T2 - Vascular Biology
UR -
UR -
UR -
VL - 1
ER -