Imperial College London

DrGaborFoldes

Faculty of MedicineNational Heart & Lung Institute

Research Fellow
 
 
 
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Contact

 

g.foldes

 
 
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Location

 

ICTEM buildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kosztin:2016:10.1080/1354750X.2016.1217931,
author = {Kosztin, A and Széplaki, G and Kovács, A and Földes, G and Szokodi, I and Nagy, KV and Kutyifa, V and Fórizs, É and Végh, EM and Gellér, L and Becker, D and Aradi, D and Merkely, B},
doi = {10.1080/1354750X.2016.1217931},
journal = {Biomarkers},
pages = {279--286},
title = {Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy},
url = {http://dx.doi.org/10.1080/1354750X.2016.1217931},
volume = {22},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - CONTEXT: Assessment of response to cardiac resynchronization therapy (CRT) is essential. OBJECTIVE: To assess the predictive value of CT-apelin together with NT-proBNP in patients undergoing CRT. METHODS: Serum CT-apelin and NT-proBNP were measured by ELISA before, and 6-month after CRT. Primary endpoint was non-response (<4% increase in LVEF) after 6-month. RESULTS: From 81 patients, 15 proved to be non-responders. Six-month CT-apelin was superior compared to NT-proBNP in identifying non-responders by multivariate ROC (CT-apelin:p = 0.01, NT-proBNP:p = 0.13) and by logistic regression (CT-apelin:p = 0.01, NT-proBNP:p = 0.41) analyzes. CONCLUSION: Six-month CT-apelin might be valuable novel biomarker in identifying non-responders to CRT that was superior to NT-proBNP.
AU - Kosztin,A
AU - Széplaki,G
AU - Kovács,A
AU - Földes,G
AU - Szokodi,I
AU - Nagy,KV
AU - Kutyifa,V
AU - Fórizs,É
AU - Végh,EM
AU - Gellér,L
AU - Becker,D
AU - Aradi,D
AU - Merkely,B
DO - 10.1080/1354750X.2016.1217931
EP - 286
PY - 2016///
SN - 1366-5804
SP - 279
TI - Impact of CT-apelin and NT-proBNP on identifying non-responders to cardiac resynchronization therapy
T2 - Biomarkers
UR - http://dx.doi.org/10.1080/1354750X.2016.1217931
UR - http://hdl.handle.net/10044/1/38646
VL - 22
ER -