Imperial College London
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ProfessorGadFrankel

Faculty of Natural Sciences, Department of Life Sciences

Professor of Molecular Pathogenesis
 
 
 
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Contact

 

+44 (0)20 7594 5253g.frankel

 
 
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Location

 

1.46Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

277 results found

Crepin VF, Prasannan S, Shaw RK, Wilson RK, Creasey E, Abe CM, Knutton S, Frankel G, Matthews Set al., 2005, Structural and functional studies of the enteropathogenic <i>Escherichia coli</i> type III needle complex protein EscJ, MOLECULAR MICROBIOLOGY, Vol: 55, Pages: 1658-1670, ISSN: 0950-382X

Journal article

Shaw RK, Cleary J, Murphy MS, Frankel G, Knutton Set al., 2005, Interaction of enteropathogenic <i>Escherichia coli</i> with human intestinal mucosa:: Role of effector proteins in brush border remodeling and formation of attaching and effacing lesions, INFECTION AND IMMUNITY, Vol: 73, Pages: 1243-1251, ISSN: 0019-9567

Journal article

Dahan S, Wiles S, La Ragione RM, Best A, Woodward MJ, Stevens MP, Shaw RK, Chong YW, Knutton S, Phillips A, Frankel Get al., 2005, EspJ is a prophage-carried type III effector protein of attaching and effacing pathogens that modulates infection dynamics, INFECTION AND IMMUNITY, Vol: 73, Pages: 679-686, ISSN: 0019-9567

Journal article

Chen HD, Frankel G, 2005, Enteropathogenic <i>Escherichia coli</i>:: unravelling pathogenesis, FEMS MICROBIOLOGY REVIEWS, Vol: 29, Pages: 83-98, ISSN: 0168-6445

Journal article

Zhang LH, Chaudhuri RR, Constantinidou C, Hobman JL, Patel MD, Jones AC, Sarti D, Roe AJ, Vlisidou I, Shaw RK, Falciani F, Stevens MP, Gally DL, Knutton S, Frankel G, Penn CW, Pallen MJet al., 2004, Regulators encoded in the <i>Escherichia coli</i> type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic <i>E</i>. coli O157:H7, INFECTION AND IMMUNITY, Vol: 72, Pages: 7282-7293, ISSN: 0019-9567

Journal article

Shaw DJ, Jenkins C, Pearce MC, Cheasty T, Gunn GJ, Dougan G, Smith HR, Woolhouse AEJ, Frankel Get al., 2004, Shedding patterns of verocytotoxin-producing <i>Escherichia coli</i> strains in a cohort of calves and their dams on a Scottish beef farm, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol: 70, Pages: 7456-7465, ISSN: 0099-2240

Journal article

Garmendia J, Phillips AD, Carlier MF, Chong YW, Schüller S, Marches O, Dahan S, Oswald E, Shaw RK, Knutton S, Frankel Get al., 2004, TccP is an enterohaemorrhagic <i>Escherichia coli</i> O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 1167-1183, ISSN: 1462-5814

Journal article

Petrovska L, Aspinall RJ, Barber L, Clare S, Simmons CP, Stratford R, Khan SA, Lemoine NR, Frankel G, Holden DW, Dougan Get al., 2004, <i>Salmonella enterica</i> serovar Typhimurium interaction with dendritic cells:: impact of the <i>sifA</i> gene, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 1071-1084, ISSN: 1462-5814

Journal article

Mundy R, Jenkins C, Yu J, Smith H, Frankel Get al., 2004, Distribution of <i>espl</i> among clinical enterohaemorrhagic and enteropathogenic <i>Escherichia coli</i> isolates, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 53, Pages: 1145-1149, ISSN: 0022-2615

Journal article

Prasannan S, Simpson P, Wilson RK, Crepin VF, Frankel G, Matthews Set al., 2004, Letter to the Editor:: <SUP>1</SUP>H, <SUP>13</SUP>C, and <SUP>15</SUP>N resonance assignments of the EscJ protein, a structural component of the Type III secretion system of enteropathogenic <i>E-coli</i> (EPEC), JOURNAL OF BIOMOLECULAR NMR, Vol: 30, Pages: 387-388, ISSN: 0925-2738

Journal article

Li CKF, Pender SLF, Pickard KM, Chance V, Holloway JA, Huett A, Gonçalves NS, Mudgett JS, Dougan G, Frankel G, MacDonald TTet al., 2004, Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice, JOURNAL OF IMMUNOLOGY, Vol: 173, Pages: 5171-5179, ISSN: 0022-1767

Journal article

Haque A, Bowe F, Fitzhenry RJ, Frankel G, Thomson M, Heuschkel R, Murch S, Stevens MP, Wallis TS, Phillips AD, Dougan Get al., 2004, Early interactions of <i>Salmonella enterica</i> serovar <i>typhimurium</i> with human small intestinal epithelial explants, GUT, Vol: 53, Pages: 1424-1430, ISSN: 0017-5749

Journal article

Wiles S, Clare S, Harker J, Huett A, Young D, Dougan G, Frankel Get al., 2004, Organ specificity, colonization and clearance dynamics <i>in vivo</i> following oral challenges with the murine pathogen <i>Citrobacter rodentium</i>, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 963-972, ISSN: 1462-5814

Journal article

Dahan S, Knutton S, Shaw RK, Crepin VF, Dougan G, Frankel Get al., 2004, Transcriptome of enterohemorrhagic <i>Escherichia coli</i> O157 adhering to eukaryotic plasma membranes, INFECTION AND IMMUNITY, Vol: 72, Pages: 5452-5459, ISSN: 0019-9567

Journal article

Ramboarina S, Fernandes P, Simpson P, Frankel G, Donnenberg M, Matthews Set al., 2004, Letter to the Editor:: Complete resonance assignments of bundlin (BfpA) from the bundle-forming pilus of enteropathogenic <i>Escherichia coli</i>, JOURNAL OF BIOMOLECULAR NMR, Vol: 29, Pages: 427-428, ISSN: 0925-2738

Journal article

Shamaei-Tousi A, Cahill R, Frankel G, 2004, Interaction between protein subunits of the type IV secretion system of <i>Bartonella henselae</i>, JOURNAL OF BACTERIOLOGY, Vol: 186, Pages: 4796-4801, ISSN: 0021-9193

Journal article

O'Connell CB, Creasey EA, Knutton S, Elliott S, Crowther LJ, Luo WS, Albert MJ, Kaper JB, Frankel G, Donnenberg MSet al., 2004, SepL, a protein required for enteropathogenic <i>Escherichia coli</i> type III translocation, interacts with secretion component SepD, MOLECULAR MICROBIOLOGY, Vol: 52, Pages: 1613-1625, ISSN: 0950-382X

Journal article

Mundy R, Petrovska L, Smollett K, Simpson N, Wilson RK, Yu J, Tu XL, Rosenshine I, Clare S, Dougan G, Frankel Get al., 2004, Identification of a novel <i>Citrobacter rodentium</i> type III secreted protein, EspI, and roles of this and other secreted proteins in infection, INFECTION AND IMMUNITY, Vol: 72, Pages: 2288-2302, ISSN: 0019-9567

Journal article

Cleary J, Lai LC, Shaw RK, Straatman-Iwanowska A, Donnenberg MS, Frankel G, Knutton Set al., 2004, Enteropathogenic <i>Escherichia coli</i> (EPEC) adhesion to intestinal epithelial cells:: role of bundle-forming pili (BFP), EspA filaments and intimin, MICROBIOLOGY-SGM, Vol: 150, Pages: 527-538, ISSN: 1350-0872

Journal article

Pearce MC, Jenkins C, Vali L, Smith AW, Knight HI, Cheasty T, Smith HR, Gunn GJ, Woolhouse MEJ, Amyes SGB, Frankel Get al., 2004, Temporal shedding patterns and virulence factors of <i>Escherichia coli</i> serogroups O26, O103, O111, O145, and O157 in a cohort of beef calves and their dams, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol: 70, Pages: 1708-1716, ISSN: 0099-2240

Journal article

Schüller S, Frankel G, Phillips AD, 2004, Interaction of Shiga toxin from <i>Escherichia coli</i> with human intestinal epithelial cell lines and explants:: Stx2 induces epithelial damage in organ culture, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 289-301, ISSN: 1462-5814

Journal article

Batchelor M, Guignot J, Patel A, Cummings N, Cleary J, Knutton S, Holden DW, Connerton I, Frankel Get al., 2004, Involvement of the intermediate filament protein cytokeratin-18 in actin pedestal formation during EPEC infection, EMBO REPORTS, Vol: 5, Pages: 104-109, ISSN: 1469-221X

Journal article

Creasey EA, Friedberg D, Shaw RK, Umanski T, Knutton S, Rosenshine I, Frankel Get al., 2003, CesAB is an enteropathogenic <i>Escherichia coli</i> chaperone for the type-III translocator proteins EspA and EspB, MICROBIOLOGY-SGM, Vol: 149, Pages: 3639-3647, ISSN: 1350-0872

Journal article

Jenkins C, Willshaw GA, Evans J, Cheasty T, Chart H, Shaw DJ, Dougan G, Frankel G, Smith HRet al., 2003, Subtyping of virulence genes in verocytotoxin-producing <i>Escherichia coli</i> (VTEC) other than serogroup O157 associated with disease in the United Kingdom, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 52, Pages: 941-947, ISSN: 0022-2615

Journal article

Simmons CP, Clare S, Ghaem-Maghami M, Uren TK, Rankin J, Huett A, Goldin R, Lewis DJ, MacDonald TT, Strugnell RA, Frankel G, Dougan Get al., 2003, Central role for B lymphocytes and CD4<SUP>+</SUP> T cells in immunity to infection by the attaching and effacing pathogen <i>Citrobacter rodentium</i>, INFECTION AND IMMUNITY, Vol: 71, Pages: 5077-5086, ISSN: 0019-9567

Journal article

Jenkins C, Lawson AJ, Cheasty T, Willshaw GA, Wright P, Dougan G, Frankel G, Smith HRet al., 2003, Subtyping intimin genes from enteropathogenic <i>Escherichia coli</i> associated with outbreaks and sporadic cases in the United Kingdom and Eire, MOLECULAR AND CELLULAR PROBES, Vol: 17, Pages: 149-156, ISSN: 0890-8508

Journal article

Creasey EA, Delahay RM, Daniell SJ, Frankel Get al., 2003, Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic <i>Escherichia coli</i>, MICROBIOLOGY-SGM, Vol: 149, Pages: 2093-2106, ISSN: 1350-0872

Journal article

Daniell SJ, Kocsis E, Morris E, Knutton S, Booy FR, Frankel Get al., 2003, 3D structure of EspA filaments from enteropathogenic <i>Escherichia coli</i>, MOLECULAR MICROBIOLOGY, Vol: 49, Pages: 301-308, ISSN: 0950-382X

Journal article

West NP, Sansonetti PJ, Frankel G, Tang CMet al., 2003, Finding your niche: what has been learnt from STM studies on GI colonization, TRENDS IN MICROBIOLOGY, Vol: 11, Pages: 338-344, ISSN: 0966-842X

Journal article

Mundy R, Pickard D, Wilson RK, Simmons CP, Dougan G, Frankel Get al., 2003, Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of <i>Citrobacter rodentium</i>, MOLECULAR MICROBIOLOGY, Vol: 48, Pages: 795-809, ISSN: 0950-382X

Journal article

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