Imperial College London
Portrait Picture

Professor Guido Franzoso

Faculty of Medicine, Department of Immunology and Inflammation

Chair in Inflammation and Signal Transduction
 
 
 
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Contact

 

+44 (0)20 3313 8421g.franzoso Website

 
 
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Assistant

 

Miss Anjli Jagpal +44 (0)20 3313 3152

 
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Location

 

5N1Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Capece:2022:10.1016/j.it.2022.07.004,
author = {Capece, D and Verzella, D and Flati, I and Arboretto, P and Cornice, J and Franzoso, G},
doi = {10.1016/j.it.2022.07.004},
journal = {Trends in Immunology},
pages = {757--775},
title = {NF-κB: blending metabolism, immunity, and inflammation},
url = {http://dx.doi.org/10.1016/j.it.2022.07.004},
volume = {43},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The procurement and management of nutrients and ability to fight infections are fundamental requirements for survival. These defense responses are bioenergetically costly, requiring the immune system to balance protection against pathogens with the need to maintain metabolic homeostasis. NF-κB transcription factors are central regulators of immunity and inflammation. Over the last two decades, these factors have emerged as a pivotal node coordinating the immune and metabolic systems in physiology and the etiopathogenesis of major threats to human health, including cancer, autoimmunity, chronic inflammation, and others. In this review, we discuss recent advances in understanding how NF-κB-dependent metabolic programs control inflammation, metabolism, and immunity and how improved knowledge of them may lead to better diagnostics and therapeutics for widespread human diseases.
AU  - Capece,D
AU  - Verzella,D
AU  - Flati,I
AU  - Arboretto,P
AU  - Cornice,J
AU  - Franzoso,G
DO  - 10.1016/j.it.2022.07.004
EP  - 775
PY  - 2022///
SN  - 0167-5699
SP  - 757
TI  - NF-κB: blending metabolism, immunity, and inflammation
T2  - Trends in Immunology
UR  - http://dx.doi.org/10.1016/j.it.2022.07.004
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35965153
UR  - http://hdl.handle.net/10044/1/99651
VL  - 43
ER  -
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