Imperial College London

ProfessorGeorgiosKassiotis

Faculty of MedicineDepartment of Infectious Disease

Professor of Retrovirology
 
 
 
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Contact

 

g.kassiotis Website

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Buck:2021:10.12688/wellcomeopenres.16517.2,
author = {Buck, MD and Poirier, EZ and Cardoso, A and Frederico, B and Canton, J and Barrell, S and Beale, R and Byrne, R and Caidan, S and Crawford, M and Cubitt, L and Gandhi, S and Goldstone, R and Grant, PR and Gulati, K and Hindmarsh, S and Howell, M and Hubank, M and Instrell, R and Jiang, M and Kassiotis, G and Lu, W-T and MacRae, JI and Martini, I and Miller, D and Moore, D and Nastouli, E and Nicod, J and Nightingale, L and Olsen, J and Oomatia, A and O'Reilly, N and Rideg, A and Song, O-R and Strange, A and Swanton, C and Turajlic, S and Wu, M and Reis, e Sousa C and Crick, COVID-19 Consortium},
doi = {10.12688/wellcomeopenres.16517.2},
journal = {Wellcome Open Res},
title = {SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay.},
url = {http://dx.doi.org/10.12688/wellcomeopenres.16517.2},
volume = {6},
year = {2021}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - The ongoing pandemic of SARS-CoV-2 calls for rapid and cost-effective methods to accurately identify infected individuals. The vast majority of patient samples is assessed for viral RNA presence by RT-qPCR. Our biomedical research institute, in collaboration between partner hospitals and an accredited clinical diagnostic laboratory, established a diagnostic testing pipeline that has reported on more than 252,000 RT-qPCR results since its commencement at the beginning of April 2020. However, due to ongoing demand and competition for critical resources, alternative testing strategies were sought. In this work, we present a clinically-validated procedure for high-throughput SARS-CoV-2 detection by RT-LAMP that is robust, reliable, repeatable, specific, and inexpensive.
AU - Buck,MD
AU - Poirier,EZ
AU - Cardoso,A
AU - Frederico,B
AU - Canton,J
AU - Barrell,S
AU - Beale,R
AU - Byrne,R
AU - Caidan,S
AU - Crawford,M
AU - Cubitt,L
AU - Gandhi,S
AU - Goldstone,R
AU - Grant,PR
AU - Gulati,K
AU - Hindmarsh,S
AU - Howell,M
AU - Hubank,M
AU - Instrell,R
AU - Jiang,M
AU - Kassiotis,G
AU - Lu,W-T
AU - MacRae,JI
AU - Martini,I
AU - Miller,D
AU - Moore,D
AU - Nastouli,E
AU - Nicod,J
AU - Nightingale,L
AU - Olsen,J
AU - Oomatia,A
AU - O'Reilly,N
AU - Rideg,A
AU - Song,O-R
AU - Strange,A
AU - Swanton,C
AU - Turajlic,S
AU - Wu,M
AU - Reis,e Sousa C
AU - Crick,COVID-19 Consortium
DO - 10.12688/wellcomeopenres.16517.2
PY - 2021///
SN - 2398-502X
TI - SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay.
T2 - Wellcome Open Res
UR - http://dx.doi.org/10.12688/wellcomeopenres.16517.2
UR - https://www.ncbi.nlm.nih.gov/pubmed/34095506
VL - 6
ER -