Imperial College London
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DrGaryfallosKonstantinoudis

Faculty of Medicine, School of Public Health

Imperial College Research Fellowship
 
 
 
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g.konstantinoudis Website

 
 
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Location

 

531Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Riesen:2018:10.1136/bmjopen-2017-021006,
author = {Riesen, M and Konstantinoudis, G and Lang, P and Low, N and Hatz, C and Maeusezahl, M and Spaar, A and Buhlmann, M and Spycher, BD and Althaus, CL},
doi = {10.1136/bmjopen-2017-021006},
journal = {BMJ Open},
pages = {1--9},
title = {Exploring variation in human papillomavirus vaccination uptake in Switzerland: a multilevel spatial analysis of a national vaccination coverage survey},
url = {http://dx.doi.org/10.1136/bmjopen-2017-021006},
volume = {8},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objective Understanding the factors that influence human papillomavirus (HPV) vaccination uptake is critically important to the design of effective vaccination programmes. In Switzerland, HPV vaccination uptake (≥1 dose) by age 16 years among women ranges from 31% to 80% across 26 cantons (states). Our objective was to identify factors that are associated with the spatial variation in HPV vaccination uptake.Methods We used cross-sectional data from the Swiss National Vaccination Coverage Survey 2009–2016 on HPV vaccination status (≥1 dose) of 14–17-year-old girls, their municipality of residence and their nationality for 21 of 26 cantons (n=8965). We examined covariates at municipality level: language, degree of urbanisation, socioeconomic position, religious denomination, results of a vote about vaccination laws as a proxy for vaccine scepticism and, at cantonal level, availability of school-based vaccination and survey period. We used a series of conditional autoregressive models to assess the effects of covariates while accounting for variability between cantons and municipal-level spatial autocorrelation.Results In the best-fit model, living in cantons that have school-based vaccination (adjusted OR 2.51; 95% credible interval 1.77 to 3.56) was associated with increased uptake, while living in municipalities with lower acceptance of vaccination laws was associated with lower HPV vaccination uptake (OR 0.61; 95% credible interval 0.50 to 0.73). Overall, the covariates explained 88% of the municipal-level variation in uptake.Conclusions In Switzerland, both cantons and community opinion about vaccination play a prominent role in the variation in HPV vaccination uptake. To increase uptake, efforts should be made to mitigate vaccination scepticism and to encourage school-based vaccination.
AU  - Riesen,M
AU  - Konstantinoudis,G
AU  - Lang,P
AU  - Low,N
AU  - Hatz,C
AU  - Maeusezahl,M
AU  - Spaar,A
AU  - Buhlmann,M
AU  - Spycher,BD
AU  - Althaus,CL
DO  - 10.1136/bmjopen-2017-021006
EP  - 9
PY  - 2018///
SN  - 2044-6055
SP  - 1
TI  - Exploring variation in human papillomavirus vaccination uptake in Switzerland: a multilevel spatial analysis of a national vaccination coverage survey
T2  - BMJ Open
UR  - http://dx.doi.org/10.1136/bmjopen-2017-021006
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000435567200138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://bmjopen.bmj.com/content/8/5/e021006
UR  - http://hdl.handle.net/10044/1/73838
VL  - 8
ER  -
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