Imperial College London
Alternate

Professor Graham P Taylor

Faculty of Medicine, Department of Infectious Disease

Professor of Human Retrovirology
 
 
 
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Contact

 

+44 (0)20 7594 3910g.p.taylor Website

 
 
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Location

 

443Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Einsiedel:2021:10.1186/s12977-020-00543-z,
author = {Einsiedel, L and Chiong, F and Jersmann, H and Taylor, GP},
doi = {10.1186/s12977-020-00543-z},
journal = {Retrovirology},
title = {Human T-cell leukaemia virus type 1 associated pulmonary disease: clinical and pathological features of an under-recognised complication of HTLV-1 infection},
url = {http://dx.doi.org/10.1186/s12977-020-00543-z},
volume = {18},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The lung is one of several organs that can be affected by HTLV-1 mediated inflammation. Pulmonary inflammation associated with HTLV-1 infection involves the interstitium, airways and alveoli, resulting in several clinical entities including interstitial pneumonias, bronchiolitis and alveolitis, depending on which structures are most affected. Augmentation of the inflammatory effects of HTLV-1 infected lymphocytes by recruitment of other inflammatory cells in a positive feedback loop is likely to underlie the pathogenesis of HTLV-1 associated pulmonary disease, as has been proposed for HTLV-1 associated myelopathy. In contrast to the conclusions of early case series, HTLV-1 associated pulmonary disease can be associated with significant parenchymal damage, which may progress to bronchiectasis where this involves the airways. Based on our current understanding of HTLV-1 associated pulmonary disease, diagnostic criteria are proposed.
AU  - Einsiedel,L
AU  - Chiong,F
AU  - Jersmann,H
AU  - Taylor,GP
DO  - 10.1186/s12977-020-00543-z
PY  - 2021///
SN  - 1742-4690
TI  - Human T-cell leukaemia virus type 1 associated pulmonary disease: clinical and pathological features of an under-recognised complication of HTLV-1 infection
T2  - Retrovirology
UR  - http://dx.doi.org/10.1186/s12977-020-00543-z
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33407607
UR  - http://hdl.handle.net/10044/1/85608
VL  - 18
ER  -
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