Imperial College London
Alternate

ProfessorGeorgePapadakis

Faculty of Engineering, Department of Aeronautics

Professor of Aerodynamics
 
 
 
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Contact

 

+44 (0)20 7594 5080g.papadakis

 
 
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Location

 

331City and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Papadakis:2019:10.1016/j.jfluidstructs.2019.06.003,
author = {Papadakis, G and Raspaud, J},
doi = {10.1016/j.jfluidstructs.2019.06.003},
journal = {Journal of Fluids and Structures},
pages = {352--366},
title = {Wave propagation in stenotic vessels; theoretical analysis and comparison between 3D and 1D fluid–structure-interaction models},
url = {http://dx.doi.org/10.1016/j.jfluidstructs.2019.06.003},
volume = {88},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to approximate the exact geometry of the constriction (length and degree of stenosis), we can construct a model that can be solved analytically and can approximate with excellent accuracy the response of the original vessel for a wide range of physiologically relevant frequencies. We then proceed to compare the 1D results with full 3D FSI results from the literature for parameters corresponding to an idealized stenotic carotid artery. We find excellent matching with the volume flow rare over the cardiac cycle (less than 1% error). Using results from DNS simulations to parametrize the velocity profile in the stenotic region, we manage to predict also the pressure distribution with small error (a few percentage points). The method proposed in the paper can be used to approximate vessels of arbitrary shape profile and can be extended to cover the whole cardiovascular tree. Recursive expressions make the solution very fast and open the possibility of carrying out sensitivity and uncertainty quantification studies that require thousands (or even millions) of simulations with minimal cost.
AU  - Papadakis,G
AU  - Raspaud,J
DO  - 10.1016/j.jfluidstructs.2019.06.003
EP  - 366
PY  - 2019///
SN  - 0889-9746
SP  - 352
TI  - Wave propagation in stenotic vessels; theoretical analysis and comparison between 3D and 1D fluid–structure-interaction models
T2  - Journal of Fluids and Structures
UR  - http://dx.doi.org/10.1016/j.jfluidstructs.2019.06.003
UR  - http://hdl.handle.net/10044/1/70858
VL  - 88
ER  -
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