157 results found
GUTTERIDGE JMC, QUINLAN GJ, CLARK I, et al., 1985, ALUMINUM SALTS ACCELERATE PEROXIDATION OF MEMBRANE-LIPIDS STIMULATED BY IRON SALTS, BIOCHIMICA ET BIOPHYSICA ACTA, Vol: 835, Pages: 441-447, ISSN: 0006-3002
GUTTERIDGE JMC, QUINLAN GJ, 1985, FREE-RADICAL DAMAGE TO DEOXYRIBOSE BY ANTHRACYCLINE, AUREOLIC ACID AND AMINOQUINONE ANTITUMOUR ANTIBIOTICS - AN ESSENTIAL REQUIREMENT FOR IRON, SEMIQUINONES AND HYDROGEN-PEROXIDE, BIOCHEMICAL PHARMACOLOGY, Vol: 34, Pages: 4099-4103, ISSN: 0006-2952
GUTTERIDGE JMC, QUINLAN GJ, WILKINS S, 1984, MITOMYCIN C-INDUCED DEOXYRIBOSE DEGRADATION INHIBITED BY SUPEROXIDE-DISMUTASE - A REACTION INVOLVING IRON, HYDROXYL AND SEMIQUINONE RADICALS, FEBS LETTERS, Vol: 167, Pages: 37-41, ISSN: 0014-5793
THOMAS AH, QUINLAN GJ, GUTTERIDGE JMC, 1984, ASSAY OF DOXORUBICIN AND 4'-EPIDOXORUBICIN BY REVERSED-PHASE ION-PAIR CHROMATOGRAPHY, JOURNAL OF CHROMATOGRAPHY, Vol: 299, Pages: 489-494, ISSN: 0021-9673
Gutteridge JM, Quinlan GJ, 1983, Malondialdehyde formation from lipid peroxides in the thiobarbituric acid test: the role of lipid radicals, iron salts, and metal chelators., J Appl Biochem, Vol: 5, Pages: 293-299, ISSN: 0161-7354
Most of the chromogen formed when peroxidized material is heated with thiobarbituric acid (TBA) can be ascribed to a colored complex formed between malondialdehyde (MDA) and TBA. Even when little MDA is present, large amounts of MDA-TBA adduct can be formed. This is because lipid peroxides break down to release MDA during the test conditions. Iron is not essential for the breakdown of the peroxides but is essential for the formation of TBA reactivity. This can be related to the ability of iron to decompose lipid peroxides with the release of peroxy radicals, which are precursors of MDA. These peroxy radicals, when released, can initiate further peroxidation during the heating stage of the TBA test. Fatty acids in the absence of lipid peroxides do not undergo significant peroxidation during the acid-heating stage of the TBA test.
GUTTERIDGE JMC, BEARD APC, QUINLAN GJ, 1983, SUPEROXIDE-DEPENDENT LIPID-PEROXIDATION - PROBLEMS WITH THE USE OF CATALASE AS A SPECIFIC PROBE FOR FENTON-DERIVED HYDROXYL RADICALS, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Vol: 117, Pages: 901-907, ISSN: 0006-291X
Thomas AH, Pharm B, Newland P, et al., 1981, Identification and determination of the qualitative composition of nystatin using thin-layer chromatography and high-performance liquid chromatography, Journal of Chromatography A, Vol: 216, Pages: 367-373, ISSN: 0021-9673
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