Publications
173 results found
Pantelidis P, Higgs D, Jagelman TAJ, et al., 2008, ATYPICAL MYCOBACTERIA IN SARCOIDOSIS BRONCHOALVEOLAR LAVAGE CELL PELLETS, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: A133-A133, ISSN: 0040-6376
Callister ME, Pinhu L, Catley MC, et al., 2008, PMX464, a thiol-reactive quinol and putative thioredoxin inhibitor, inhibits NF-κB-dependent proinflammatory activation of alveolar epithelial cells, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 155, Pages: 661-672, ISSN: 0007-1188
- Author Web Link
- Open Access Link
- Cite
- Citations: 13
Lagan AL, Quinlan GJ, Mumby S, et al., 2008, Variation in iron homeostasis genes between patients with ARDS and healthy control subjects, CHEST, Vol: 133, Pages: 1302-1311, ISSN: 0012-3692
- Author Web Link
- Cite
- Citations: 28
Quinlan GJ, Lagan AL, Evans TW, 2008, Haem oxygenase: A model for therapeutic intervention, INTENSIVE CARE MEDICINE, Vol: 34, Pages: 595-597, ISSN: 0342-4642
- Author Web Link
- Cite
- Citations: 5
Lagan AL, Melley DD, Evans TW, et al., 2008, Pathogenesis of the systemic inflammatory syndrome and acute lung injury: role of iron mobilization and decompartmentalization, AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol: 294, Pages: L161-L174, ISSN: 1040-0605
- Author Web Link
- Cite
- Citations: 42
MacCallum NS, Gordon SE, Quinlan GJ, et al., 2008, Systemic inflammatory response syndrome post cardiac surgery: a useful concept?, Crit Care, International Symposium on Intensive Care and Emergency Medicine, Pages: P258-P258
MacCallum NS, Quinlan GJ, Evans TW, 2007, The role of neutrophil-derived myeloperoxidase in organ dysfunction and sepsis, Intensive Care Medicine: Annual Update 2007, Pages: 173-187, ISBN: 9780387495170
Neutrophils are the first cells to be activated in the host immune response to infection or injury and are critical cellular effectors in both humoral and innate immunity, central to the pathogenesis of sepsis and multi-organ dysfunction [1]. However, the neutrophil capacity for bacterial killing lacks selectivity, despite stringent regulation, and thereby carries the potential to inflict collateral damage to, and destruction of host tissue [2]. Host tissue damage characterizes both autoimmune and inflammatory conditions and may arise via a variety of mechanisms including premature neutrophil activation during migration, extracellular release of cytotoxic molecules during microbial killing, removal of infected or damaged host cells or debris during host tissue remodeling, and failure to terminate acute inflammatory responses [3]. Sepsis-induced neutrophil mediated tissue injury has been demonstrated in a variety of organs including the lungs [4, 5], kidneys [6], and liver [7]. © 2007 Springer Science + Business Media Inc.
MacCallum NS, Gordon SE, Quinlan GJ, et al., 2007, The systemic inflammatory response syndrome following cardiac surgery, 80th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 928-928, ISSN: 0009-7322
- Author Web Link
- Cite
- Citations: 1
Melley DD, Finney SJ, Elia A, et al., 2007, Arterial carboxyhemoglobin level and outcome in critically ill patients, CRITICAL CARE MEDICINE, Vol: 35, Pages: 1882-1887, ISSN: 0090-3493
- Author Web Link
- Cite
- Citations: 39
MacCallum N, Quinlan G, Evans T, 2007, Detection of myeloperoxidase-caeruloplasmin complex in vitro: Impact on redox imbalance, Publisher: BIRKHAUSER VERLAG AG, Pages: S102-S102, ISSN: 1023-3830
Callister ME, Burke-Gaffney A, Quinlan GJ, et al., 2007, Persistently low plasma thioredoxin is associated with meningococcal septic shock in children, INTENSIVE CARE MEDICINE, Vol: 33, Pages: 364-367, ISSN: 0342-4642
- Author Web Link
- Cite
- Citations: 9
Melley DD, Lagan AL, Quinlan GJ, et al., 2006, Heme oxygenase-1 is induced in human neutrophils following surgery requiring cardiopulmonary bypass, Winter Meeting of the British-Thoracic-Society/British-Lung-Foundation (BTS/BLF), Publisher: B M J PUBLISHING GROUP, Pages: II50-II51, ISSN: 0040-6376
Callister ME, Burke-Gaffney A, Quinlan GJ, et al., 2006, Extracellular thioredoxin levels are increased in patients with acute lung injury, THORAX, Vol: 61, Pages: 521-527, ISSN: 0040-6376
- Author Web Link
- Cite
- Citations: 63
Melley DD, Finney SJ, Quinlan GJ, et al., 2006, Arterial Carboxyhemoglobin and Intensive Care Outcome, Am J Respir Crit Care Med, American Thoracic Society International Congress, Pages: A427-A427
Melley DD, Quinlan GJ, Evans TW, 2005, The divergent effects of heme on neutrophil apoptosis, Winter Meeting of the British-Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: II80-II80, ISSN: 0040-6376
- Author Web Link
- Cite
- Citations: 1
Razavi HM, Wang LF, Weicker S, et al., 2005, Pulmonary oxidant stress in murine sepsis is due to inflammatory cell nitric oxide, CRITICAL CARE MEDICINE, Vol: 33, Pages: 1333-1339, ISSN: 0090-3493
- Author Web Link
- Cite
- Citations: 53
Quinlan GJ, Martin GS, Evans TW, 2005, Albumin: Biochemical properties and therapeutic potential, HEPATOLOGY, Vol: 41, Pages: 1211-1219, ISSN: 0270-9139
- Author Web Link
- Cite
- Citations: 621
Melley DD, Evans TW, Quinlan GJ, 2005, Redox regulation of neutrophil apoptosis and the systemic inflammatory response syndrome, CLINICAL SCIENCE, Vol: 108, Pages: 413-424, ISSN: 0143-5221
- Author Web Link
- Cite
- Citations: 58
Mumby S, Upton RL, Chen Y, et al., 2004, Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome, CRITICAL CARE MEDICINE, Vol: 32, Pages: 1130-1135, ISSN: 0090-3493
- Author Web Link
- Cite
- Citations: 68
Quinlan GJ, Mumby S, Martin GS, et al., 2004, Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury, CRITICAL CARE MEDICINE, Vol: 32, Pages: 755-759, ISSN: 0090-3493
- Author Web Link
- Cite
- Citations: 134
Moloney ED, Mumby SE, Gajdocsi R, et al., 2004, Exhaled breath condensate detects markers of pulmonary inflammation after cardiothoracic surgery, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 169, Pages: 64-69, ISSN: 1073-449X
- Author Web Link
- Cite
- Citations: 54
Callister MEJ, Pinhu L, Catley M, et al., 2004, Inhibition of intracellular thioredoxin activity prevents inflammatory activation of an alveolar epithelial cell line through effects on the nuclear factor-kappa B signalling pathway, Am J Respir Crit Care Med, American Thoracic Society International Congress
Sato H, Callister MEJ, Mumby S, et al., 2004, KL-6 levels are elevated in plasma from patients with acute respiratory distress syndrome, EUROPEAN RESPIRATORY JOURNAL, Vol: 23, Pages: 142-145, ISSN: 0903-1936
- Author Web Link
- Cite
- Citations: 82
Melley D, de Souza P, Quinlan G, et al., 2003, The heme oxygenase substrate analog hemin inhibits apoptosis in human neutrophils, Winter Meeting of the British Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 31-31, ISSN: 0040-6376
Moloney ED, Mumby S, Gajdocsi R, et al., 2003, Exhaled breath condensate compared to broncho-alveolar lavage for detecting lung inflammation induced by cardiothoracic surgery, Winter Meeting of the British Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 36-36, ISSN: 0040-6376
Callister MEJ, Pinhu L, Finney SJ, et al., 2003, Inhibition of intracellular thioredoxin activity prevents inflammatory activation of an alveolar epithelial cell line through effects on the nuclear factor-κ B signalling pathway, Winter Meeting of the British Thoracic-Society, Publisher: B M J PUBLISHING GROUP, Pages: 1-1, ISSN: 0040-6376
Callister MEJ, Sato H, Mumby S, et al., 2003, Kl-6 levels are elevated in plasma from patients with the acute respiratory distress syndrome, 16th Annual Congress of the European-Society-of-Intensive-Care-Medicine, Publisher: SPRINGER, Pages: S5-S5, ISSN: 0342-4642
Upton RL, Chen Y, Mumby S, et al., 2003, Variable tissue expression of transferrin receptors: relevance to acute respiratory distress syndrome, EUROPEAN RESPIRATORY JOURNAL, Vol: 22, Pages: 335-341, ISSN: 0903-1936
- Author Web Link
- Cite
- Citations: 20
Quinlan G, 2003, Antioxidant properties of albumin, Reanimation, Vol: 12, ISSN: 1624-0693
Callister MEJ, Burke-Gaffney A, Quinlan GJ, et al., 2002, Elevation of thioredoxin concentrations in plasma and broncho-alveolar lavage fluid from patients with the acute respiratory distress syndrome, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, ISSN: 0040-6376
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.