Imperial College London


Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Chair in Cell Biology



+44 (0)20 7594 3340g.rutter Website




ICTEM buildingHammersmith Campus





Job Title: Professor of Cell Biology and Functional Genomics

Research: Signal transduction in the pancreatic β-cell in health and disease - my chief focus is in using functional genomics at the cellular and whole organism level to dissect the role of genes associated with Type 2 diabetes.

Brief Biosketch: After studying for a PhD in Bristol with Dick Denton FRS on mitochondrial Ca2 signalling, I subsequently worked on the pancreatic β-cell as an MRC travelling Fellow with Claes Wollheim in Geneva. There, working collaboratively with Tullio Pozzan and Rosario Rizzuto in Padua, I established new approaches to exploring the control of insulin release at the single cell level through the use of recombinant target probes and other techniques. I then returned to Bristol, becoming a full Professor of Biochemistry in 2002, and moved to Imperial College in 2006.  

My current research is supported by Wellcome Trust Senior Investigator and Royal Society Wolfson Merit Awards, by UK Research Council and Diabetes UK grants, as well as by the European Commission Innovative Medicines Initiative in Diabetes (IMIDIA).

Prizes and Awards: I was awarded the Minkowski Prize of the European Association for the Study of Diabetes in 2004, the Juvenile Diabetes Research Foundation's Mary Jane Krugel Award (2005), a Royal Society Wolfson Research Merit Award (2011), a Wellcome Trust Senior Investigator Award (2012) and the Dorothy Hodgkin Lecturehip of Diabetes UK (2014).

Recent Publications

Research Support. Supported by Programme and other grants from the Wellcome Trust, MRC, DUK, JDRF, BBSRC, NIH, BHF and EU.

Related links to Section of Cell Biology and Functional Genomics



Tomas Catala A, Bitsi S, Manchanda Y, et al., 2023, Divergent acute versus prolonged pharmacological GLP-1R responses in adult beta cell-specific β-arrestin 2 knockout mice, Science Advances, ISSN:2375-2548

Rutter G, Surekha MV, Suneetha N, et al., 2023, Impact of COVID-19 on placental pathology, maternal and neonatal outcome in term pregnant women with high anemia prevalence – A cross-sectional study from a tertiary care hospital in southern India, Frontiers in Endocrinology, ISSN:1664-2392

Chabosseau P, Yong F, Delgadillo-Silva LF, et al., 2023, Molecular phenotyping of single pancreatic islet leader beta cells by "Flash-Seq", Life Sciences, Vol:316, ISSN:0024-3205

Avari P, Eng PC, Hu M, et al., 2023, A novel somatic mutation implicates ATP6V0D1 in proinsulin processing, Journal of the Endocrine Society, Vol:7, ISSN:2472-1972, Pages:1-5

Anindya R, Rutter GA, Meur G, 2023, New-onset type 1 diabetes and severe acute respiratory syndrome coronavirus 2 infection, Immunology and Cell Biology, ISSN:0818-9641

More Publications