My background is in theoretical physics and developmental biology. If I had to pick a general label for my main research interest, that would be quantitative developmental biology.
I am broadly interested in physical and genetic mechanisms generating “growth and form” in multicellular systems, especially through the establishment and maintenance of spatio-temporal patterns within a field of interacting cells. I view tissue development as a process of self-organization and morphogenesis as one of its emergent properties.
I believe that plants offer many experimental advantages that make them attractive model systems to address fundamental questions on multi-cellular organization.
Arabidopsis thaliana is the model system of choice in my lab, and the preferred approach is a combination of genetics, quantitative imaging and mathematical modeling.
- Senior Lecturer (2020 – present), Imperial College London, London, U.K.
- Lecturer (2012 – 2020), Imperial College London, London, U.K.
- Post-doctoral Research Associate (2005 - 2011), K. Birnbaum lab, New York University, New York, U.S.A.
- Visiting Fellow (2005 - 2011), S. Leibler lab, The Rockefeller University, New York, U.S.A.
- Post-doctoral Fellow (2003 - 2005), S. Leibler lab, The Rockefeller University, New York, U.S.A.
- Research Assistant, volunteer (1996 - 1997), M. D'Incalci lab, Istituto Mario Negri, Milan, Italy.
- Ph.D., Biology (2003). Developmental Genetics. Prof. P. Benfey lab, New York University, New York, U.S.A.
- B.Sc. / M.Phys., Physics (1995, Laurea), 110/110 with honour. Theoretical physics, Prof. L. Girardello, University of Milan, Milan, Italy.
et al., 2020, Correction to ‘Bioelectrical understanding and engineering of cell biology’, Journal of the Royal Society Interface, Vol:17, ISSN:1742-5662, Pages:1-1
et al., 2019, Linear stability analysis of morphodynamics during tissue regeneration in plants, Journal of Physics D - Applied Physics, Vol:52, ISSN:0022-3727
Kral N, Hanna Ougolnikova A, Sena G, 2016, Externally imposed electric field enhances plant root tip regeneration, Regeneration, Vol:3, ISSN:2052-4412, Pages:156-167
et al., 2001, Intercellular movement of the putative transcription factor SHR in root patterning, Nature, Vol:413, ISSN:0028-0836, Pages:307-311
Baesso P, Randall RS, Sena G, 2018, Light Sheet Fluorescence Microscopy Optimized for Long-Term Imaging of Arabidopsis Root Development., Pages:145-163