BibTex format
@inproceedings{Benfey:2003,
author = {Benfey, PN and Gallagher, K and Paquette, A and Nakajima, K and Sena, G},
pages = {523--523},
title = {Radial patterning in arabidopsis: A moving target},
year = {2003}
}
Publications
Citation
RIS format (EndNote, RefMan)
TY - CPAPER
AB - Plant embryos consist primarily of two stem-cell populations known as meristems, one that will make the root and the other that makes the shoot. Determining how the cells in these meristems are able to control their own division and the differ- entiation program of their progeny to form organs is one of the major questions of plant development. We have uncovered evi- dence for a signaling center located in the internal tissues of the Arabidopsis root that provides pattern information through cell— cell movement of a transcription factor to the surrounding cell layer. In the root of Arabidopsis, we have characterized mutations in which specific meristem cells fail to divide, or their progeny acquire the wrong identity. Analysis of mutations in the SCARE- CROW (SCR) and SHORT-ROOT (SHR) genes indicates that they are key regulators of radial patterning in the root. Both SHR and SCR are members of the GRAS family of putative transcription factors. SHR acts in a non-cell-autonomous fashion to regulate the amount of RNA that is made by the SCR gene. Analysis of SHR localization revealed protein both in the stele and in the cells immediately adjacent to it, indicating that SHR is able to move from the stele to the adjacent layer. Ectopic expression of SHR results in supernumerary cell layers and altered cell speci- fication, indicating that SHR is both necessary and sufficient for cell division and cell specification in the root meristem. Efforts to identify the mechanism of this highly regulated protein move- ment will be discussed
AU - Benfey,PN
AU - Gallagher,K
AU - Paquette,A
AU - Nakajima,K
AU - Sena,G
EP - 523
PY - 2003///
SN - 0012-1606
SP - 523
TI - Radial patterning in arabidopsis: A moving target
ER -