BibTex format
@inproceedings{Benfey:2001,
author = {Benfey, PN and Nakajima, K and Sena, G and Paquette, A},
pages = {288--288},
title = {Radial patterning in Arabidopsis: Signaling inside out},
year = {2001}
}
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TY - CPAPER
AB - In contrast to animal embryos which are miniature versions of the adult, if you look at a plant embryo it is nearly impossible to predict the form or size of the adult plant. This is because plant embryos consist primarily of two stem cell populations called meristems, one that will make the root and the other that makes the shoot. Determining how the cells in these meristems are able to control how they divide and how their progeny differentiate to form organs is one of the major questions of plant development. We have uncovered evidence for a signaling center located in the internal tissues of the Arabidopsis root that provides pattern information to the surrounding cell layers. In the root of Arabidop- sis, mutations have been found in which specific meristem cells fail to divide, or their progeny acquire the wrong identity. Analysis of mutations in the SCARECROW (SCR) and SHORT-ROOT (SHR) genes indicates that they are key regulators of radial patterning in the root. Both genes have been cloned and their expression patterns are consistent with their role in radial patterning. Analysis of tissue-specific markers indicates that SCR is primarily required for the asymmetric division that gives cortex and endodermis. The SHORT-ROOT gene is required for the asymmetric cell division responsible for formation of ground tissue as well as specification of endodermis. Both SHR and SCR are members of the GRAS family of putative transcription factors. The SHORT-ROOT gene appears to act by regulating the amount of RNA that is made by the SCARECROW gene. Surprisingly, the SHORT-ROOT gene is not expressed in the same cells as the SCARECROW gene. Instead, a novel means of cell– cell signaling appears to be responsible for the transfer of radial pattern information. Ectopic expression of SHR results in supernumerary cell layers and altered cell specification, indicating that SHR is both necessary and sufficient for cell division and cell specification in the root meristem.
AU - Benfey,PN
AU - Nakajima,K
AU - Sena,G
AU - Paquette,A
EP - 288
PY - 2001///
SN - 0012-1606
SP - 288
TI - Radial patterning in Arabidopsis: Signaling inside out
ER -