Imperial College London
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ProfessorGrahamWilliams

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Clinical Professor of Endocrinology
 
 
 
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Contact

 

+44 (0)20 3313 1383graham.williams

 
 
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Location

 

10N5Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Foessl:2021:10.3389/fendo.2021.720728,
author = {Foessl, I and Bassett, JHD and Bjornerem, A and Busse, B and Calado, A and Chavassieux, P and Christou, M and Douni, E and Fiedler, IAK and Fonseca, JE and Hassler, E and Hoegler, W and Kague, E and Karasik, D and Khashayar, P and Langdahl, BL and Leitch, VD and Lopes, P and Markozannes, G and McGuigan, FEA and Medina-Gomez, C and Ntzani, E and Oei, L and Ohlsson, C and Szulc, P and Tobias, JH and Trajanoska, K and Tuzun, S and Valjevac, A and van, Rietbergen B and Williams, GR and Zekic, T and Rivadeneira, F and Obermayer-Pietsch, B},
doi = {10.3389/fendo.2021.720728},
journal = {Frontiers in Endocrinology},
pages = {1--32},
title = {Bone phenotyping approaches in human, mice and zebrafish - expert overview of the EU cost action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork")},
url = {http://dx.doi.org/10.3389/fendo.2021.720728},
volume = {12},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - A synoptic overview of scientific methods applied in bone and associated research fields across species has yet to be published. Experts from the EU Cost Action GEMSTONE (“GEnomics of MusculoSkeletal Traits translational Network”) Working Group 2 present an overview of the routine techniques as well as clinical and research approaches employed to characterize bone phenotypes in humans and selected animal models (mice and zebrafish) of health and disease. The goal is consolidation of knowledge and a map for future research. This expert paper provides a comprehensive overview of state-of-the-art technologies to investigate bone properties in humans and animals – including their strengths and weaknesses. New research methodologies are outlined and future strategies are discussed to combine phenotypic with rapidly developing –omics data in order to advance musculoskeletal research and move towards “personalised medicine”.
AU  - Foessl,I
AU  - Bassett,JHD
AU  - Bjornerem,A
AU  - Busse,B
AU  - Calado,A
AU  - Chavassieux,P
AU  - Christou,M
AU  - Douni,E
AU  - Fiedler,IAK
AU  - Fonseca,JE
AU  - Hassler,E
AU  - Hoegler,W
AU  - Kague,E
AU  - Karasik,D
AU  - Khashayar,P
AU  - Langdahl,BL
AU  - Leitch,VD
AU  - Lopes,P
AU  - Markozannes,G
AU  - McGuigan,FEA
AU  - Medina-Gomez,C
AU  - Ntzani,E
AU  - Oei,L
AU  - Ohlsson,C
AU  - Szulc,P
AU  - Tobias,JH
AU  - Trajanoska,K
AU  - Tuzun,S
AU  - Valjevac,A
AU  - van,Rietbergen B
AU  - Williams,GR
AU  - Zekic,T
AU  - Rivadeneira,F
AU  - Obermayer-Pietsch,B
DO  - 10.3389/fendo.2021.720728
EP  - 32
PY  - 2021///
SN  - 1664-2392
SP  - 1
TI  - Bone phenotyping approaches in human, mice and zebrafish - expert overview of the EU cost action GEMSTONE ("GEnomics of MusculoSkeletal traits TranslatiOnal NEtwork")
T2  - Frontiers in Endocrinology
UR  - http://dx.doi.org/10.3389/fendo.2021.720728
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000730427000001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.frontiersin.org/articles/10.3389/fendo.2021.720728/full
UR  - http://hdl.handle.net/10044/1/94835
VL  - 12
ER  -
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