My research group studies the molecular basis of immune cell development and function. We are particularly interested in the role of the E4bp4/Nfil3 gene in NK cell development and both the function and role of the Mll gene in haematopoietic stem cell self-renewal and immune cell development.
et al., 2022, In Vitro Development of Mouse and Human NK Cells from Hematopoietic Progenitor Cells., Methods Mol Biol, Vol:2463, Pages:31-45
et al., 2020, The transcriptional repressor REV-ERB as a novel target for disease, Bioorganic & Medicinal Chemistry Letters, Vol:30, ISSN:0960-894X, Pages:127395-127395
et al., 2018, Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency., Am J Physiol Lung Cell Mol Physiol, Vol:315, Pages:L977-L990
et al., 2018, Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs, Science Signaling, Vol:11, ISSN:1945-0877
et al., 2018, Multiple levels of control determine how E4bp4/Nfil3 regulates NK cell development, Journal of Immunology, Vol:200, ISSN:0022-1767, Pages:1370-1381