Imperial College London

Professor Hugh JM Brady

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Immunology



+44 (0)20 7594 3777h.brady Website




504Sir Alexander Fleming BuildingSouth Kensington Campus





My research group studies the molecular basis of immune cell development and function.  We are particularly interested in the role of the E4bp4/Nfil3 gene in NK cell development and both the function and role of the Mll gene in haematopoietic stem cell self-renewal and immune cell development.



Ullmo I, Koksal N, Ang HYK, et al., 2022, In Vitro Development of Mouse and Human NK Cells from Hematopoietic Progenitor Cells., Methods Mol Biol, Vol:2463, Pages:31-45

Uriz-Huarte A, Date A, Ang H, et al., 2020, The transcriptional repressor REV-ERB as a novel target for disease, Bioorganic & Medicinal Chemistry Letters, Vol:30, ISSN:0960-894X, Pages:127395-127395

Rätsep MT, Moore SD, Jafri S, et al., 2018, Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency., Am J Physiol Lung Cell Mol Physiol, Vol:315, Pages:L977-L990

Rollings CM, Sinclair LV, Brady HJM, et al., 2018, Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs, Science Signaling, Vol:11, ISSN:1945-0877

Kostrzewski T, Borg AJ, Meng Y, et al., 2018, Multiple levels of control determine how E4bp4/Nfil3 regulates NK cell development, Journal of Immunology, Vol:200, ISSN:0022-1767, Pages:1370-1381

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