Imperial College London

Professor Hugh JM Brady

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Immunology
 
 
 
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Contact

 

+44 (0)20 7594 3777h.brady

 
 
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Location

 

504Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Advanced Immunology - LIFE96003

Aims

This course follows on from the 2nd year Biological Sciences Immunology course. However, as Biochemistry students have not covered so much Immunology in their 2nd year, there will be two revision lectures to begin the course. The course will cover six main topics:

1. The cellular basis of detection and killing in mammalian innate immunity and comparative evolution of immune responses.

2. The molecular basis of innate immunity in plants and how it comapres to mammalian innate immunity

3. Innate lymphoid cells – where do they come from and what do they do

4. Mechanisms of cellular immunoregulation – the development, plasticity and function of regulatory T cells

5. The role of gut microbiota in regulating immune responses and in disease

6. Cancer immunology, the role of the immune system in cancer development and how we can use immunotherapies to treat cancer

Role

Course Leader

Cell Biology and Genetics - LIFE40006

Aims

The behaviour of living cells is influenced by both their genetics and by their environment. In this module, you will explore how the genetic information in cells is expressed as a phenotype, and how this expression is regulated in response to stimuli from the cell's environment. The module will address the central information transfer pathways in the cell (replication, transcription and translation), and aims to develop your skills in analysing genetic systems in model organisms. It will familiarise you with the compartments from which eukaryotic cells are constructed and how proteins are targeted to them. We will also explore specific examples of cellular interactions: neuronal signalling, vertebrate immunity, and viral infection. In the practical work in the summer term, you will work as a team to design experiments to investigate your own hypotheses in the context of the interaction between the growth of bacterial cells and their environment. We will continue to develop both your quantitative and writing skills.

Role

Lecturer

Challenges in Cell Biology - LIFE95006

Aims

CCB will give students an understanding of current cell biology research challenges and the approaches being developed to tackle them. It will discuss areas of cell biology that are new to second year Biochemists and so complement their previous cell biology teaching as well as introduce themes that will be developed in several final year courses.  

Role

Lecturer

Immunology - LIFE95011

Aims

The course provides a detailed overview of the organisation, development and regulation of the immune system in health and disease.  It assumes a basic knowledge of cell biology and immunology. 

Role

Lecturer