Imperial College London
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Dr Harriet Kemp

Faculty of Medicine, Department of Surgery & Cancer

Clinical Lecturer
 
 
 
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Contact

 

h.kemp

 
 
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Location

 

Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Sipilä:2021:10.1515/sjpain-2020-0177,
author = {Sipilä, R and Kemp, H and Harno, H and Rice, ASC and Kalso, E},
doi = {10.1515/sjpain-2020-0177},
journal = {Scandinavian Journal of Pain},
pages = {512--521},
title = {Health-related quality of life and pain interference in two patient cohorts with neuropathic pain: breast cancer survivors and HIV patients},
url = {http://dx.doi.org/10.1515/sjpain-2020-0177},
volume = {21},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - OBJECTIVES: Persistent pain is common in HIV patients and breast cancer (BC) survivors. The aim of this study was to compare two patient groups with neuropathic pain (NP) regarding several psychological variables and Health-related Quality of Life. Although, treatment of pain is always planned individually, the knowledge of the differences and similarities between the patient groups may help us to understand more precisely the targets of the interventions for pain. METHODS: Eighty nine BC and 73 HIV patients with symptoms of neuropathic pain (patients with ≥3/7 in the Douleur Neuropathique four interview part (DN4i)) participated in a cross-sectional study. Patients completed questionnaires about mood (HADS), symptoms of insomnia (ISI), pain catastrophizing (PCS), personality (TIPI), Mental and Physical Health-related Quality of Life (M/PHrQoL, RAND/SF-36), and pain intensity and interference (BPI). Analyses were applied by using t-tests and linear regression to assess associations between the studied factors. RESULTS: HIV patients reported higher anxiety (p<0.001), depressive symptoms (p<0.001), pain catastrophizing (p<0.001) and pain interference (p<0.001), poorer sleep (p<0.001), and lower HrQoL in all dimensions compared with BC survivors. There were significant differences in personality traits extraversion, emotional stability, and agreeableness between the two patient groups. In HIV patients, pain interference (β=-0.344, p<0.001) and mood (β=-0.580, p<0.001) and in the BC group, mood (β=-0.591, p<0.001), extraversion (β=0.229, p=0.005) and sleep (β=-0.154, p=0.042) associated with MHrQoL. Pain interference (HIV β=-0.645, p<0.001, BC β=-0.491, p<0.001) and age (HIV β=-0.016, p=0.042 and BC β=-0.018, p=0.019) associated with PHrQoL in both groups, and catastrophizing in the BC group (β=-0.303, p<0.001). CONCLUSIONS: HIV patients and BC survivors with neuropathic pain, mea
AU  - Sipilä,R
AU  - Kemp,H
AU  - Harno,H
AU  - Rice,ASC
AU  - Kalso,E
DO  - 10.1515/sjpain-2020-0177
EP  - 521
PY  - 2021///
SN  - 1877-8860
SP  - 512
TI  - Health-related quality of life and pain interference in two patient cohorts with neuropathic pain: breast cancer survivors and HIV patients
T2  - Scandinavian Journal of Pain
UR  - http://dx.doi.org/10.1515/sjpain-2020-0177
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33725747
UR  - https://www.degruyter.com/document/doi/10.1515/sjpain-2020-0177/html
UR  - http://hdl.handle.net/10044/1/87732
VL  - 21
ER  -
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