Imperial College London

DrHamounRozati

Faculty of MedicineDepartment of Surgery & Cancer

Research Postgraduate
 
 
 
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h.rozati

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

11 results found

Rozati H, Paddick I, Sabin I, 2021, Three-staged stereotactic radiosurgery for brain metastases: a single institution experience, Neuro-Oncology, Vol: 23, Pages: iv20-iv21, ISSN: 1522-8517

<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Aims</jats:title> <jats:p>Stereotactic radiosurgery (SRS) using the Leksell Gamma Knife system is a commonly used modality for the treatment of brain metastases (BMs). As the size of the target volume (TV) increases, so too does the dose of radiation delivered to surrounding healthy tissue. Large BMs are therefore a contraindication to the use of SRS. Critical organs adjacent to the TV may also be a contraindication to SRS. Staged SRS was proposed as a novel method of delivering three SRS treatments at a reduced radiation dose with a gap of two weeks between each session as a way of shrinking the TV. This allows treatment of TVs otherwise considered untreatable with standard, single-fraction SRS. Little data exists in the literature as to its efficacy. The objective of this study was to evaluate the efficacy of this novel approach and to identify factors which may predict treatment failure.</jats:p> </jats:sec> <jats:sec> <jats:title>Method</jats:title> <jats:p>A retrospective analysis was undertaken at a single, tertiary Gamma Knife centre. All patients who underwent treatment of their BMs with three-staged Gamma Knife SRS from January 2014 to December 2020 were identified and included. Patient demographics and primary cancer status was ascertained. SRS treatment details for each lesion were collected, including TV, dose and dosimetric data. The percentage reduction in volume of the TVs between the first and second stage, the second and third stage and the first and third stage were calculated. Follow-up data was collected to include follow-up imaging, further intracranial treatments received and survival status. The percentage reduction in volume between each stage was demonstrated on box-and-whisker plots. Statistical significan

Journal article

Rozati H, Ferguson FJ, Rashidghamat E, Anand Get al., 2020, Delivery of high-dose radiation for recurrence of breast cancer in a patient with hidradenitis suppurativa, BMJ Case Reports, Vol: 13, Pages: e238848-e238848

<jats:p>Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterised by inflammatory nodules, abscesses, sinus tract formation and scarring. There is a lack of evidence for the use of radical radiotherapy for patients with a diagnosis of HS. A 56-year-old woman with a long-standing diagnosis of HS presented with a cutaneous local recurrence of breast cancer. Radical radiotherapy was offered despite issues with previous prolonged postoperative wound healing associated with the underlying HS. A multidisciplinary evaluation was conducted with breast surgeons, dermatologists and radiation oncologists to assess the safety of delivery of radical radiotherapy. Five weeks post radiotherapy, the patient had no significant residual symptoms from her breast cancer treatment for her HS and no escalation of treatment was required for her HS. Factors contributing to safe delivery of radical radiotherapy include medical optimisation prior to and during treatment, radiation dose, radiation technique and vigilant post-treatment surveillance.</jats:p>

Journal article

Kühnl A, Cunningham D, Hutka M, Peckitt C, Rozati H, Morano F, Chong I, Gillbanks A, Wotherspoon A, Harris M, Murray T, Chau Iet al., 2018, Rapid access clinic for unexplained lymphadenopathy and suspected malignancy: prospective analysis of 1000 patients, BMC Hematology, Vol: 18

Journal article

Rozati H, Handley T, Jayasena C, 2017, Process and Pitfalls of Sperm Cryopreservation, JOURNAL OF CLINICAL MEDICINE, Vol: 6

Journal article

Saxby H, Rozati H, Shousa S, Cleator Set al., 2016, The management of ductal carcinoma in-situ at Charing Cross Hospital, European Journal of Surgical Oncology (EJSO), Vol: 42, Pages: S221-S221, ISSN: 0748-7983

Journal article

Rozati H, Shah SP, Shah N, 2015, Smartphone Applications for the Clinical Oncologist in UK Practice, Journal of Cancer Education, Vol: 30, Pages: 367-373, ISSN: 0885-8195

Journal article

Rozati H, Zafar S, Trevatt A, Besherdas Ket al., 2014, Sa1096 How Well Do We Investigate Iron Deficiency Anaemia With Colonoscopy Following a Normal Gastroscopy?, Gastroenterology, Vol: 146, Pages: S-198, ISSN: 0016-5085

Journal article

Shah N, Shah SP, Thakrar A, Rozati Het al., 2014, An adhesion-related small bowel obstruction occurring within 36 h of a total abdominal hysterectomy and bilateral salpingo-oophorectomy, Case Reports, Vol: 2014, Pages: bcr2013201507-bcr2013201507, ISSN: 1757-790X

Journal article

Shah N, Fernandes R, Thakrar A, Rozati Het al., 2013, Diaphragmatic hernia: an unusual presentation, Case Reports, Vol: 2013, Pages: bcr2013008699-bcr2013008699, ISSN: 1757-790X

Journal article

Rozati H, Shah SP, Peng YY, 2013, Lower limb gangrene postcardiac surgery, Case Reports, Vol: 2013, Pages: bcr2012008362-bcr2012008362, ISSN: 1757-790X

Journal article

Rozati H, Jaffer ZN, Al-Hadithy N, 2012, A young man with wrist pain, BMJ, Vol: 345, Pages: e4466-e4466

Journal article

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