Imperial College London
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DrHeatherWalton

Faculty of Medicine, School of Public Health

Senior Lecturer in Environmental Health
 
 
 
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Contact

 

h.walton Website

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Atkinson:2014:10.1136/thoraxjnl-2013-204492,
author = {Atkinson, R and Kang, S and Anderson, R and Mills, I and Walton, H},
doi = {10.1136/thoraxjnl-2013-204492},
journal = {a systematic review and meta-analysis},
pages = {660--665},
title = {Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions: a systematic review and meta-analysis},
url = {http://dx.doi.org/10.1136/thoraxjnl-2013-204492},
volume = {69},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: Short-term exposure to outdoor fine particulate matter (particles with a median aerodynamic diameter <2.5 μm (PM2.5)) air pollution has been associated with adverse health effects. Existing literature reviews have been limited in size and scope.Methods: We conducted a comprehensive, systematic review and meta-analysis of 110 peer-reviewed time series studies indexed in medical databases to May 2011 to assess the evidence for associations between PM2.5 and daily mortality and hospital admissions for a range of diseases and ages. We stratified our analyses by geographical region to determine the consistency of the evidence worldwide and investigated small study bias.Results: Based upon 23 estimates for all-cause mortality, a 10µg/m3 increment in PM2.5 was associated with a 1.04% (95% CI 0.52% to 1.56%) increase in the risk of death. Worldwide, there was substantial regional variation (0.25% to 2.08%). Associations for respiratory causes of death were larger than for cardiovascular causes, 1.51% (1.01% to 2.01%) vs 0.84% (0.41% to 1.28%). Positive associations with mortality for most other causes of death and for cardiovascular and respiratory hospital admissions were also observed. We found evidence for small study bias in single-city mortality studies and in multicity studies of cardiovascular disease.Conclusions: The consistency of the evidence for adverse health effects of short-term exposure to PM2.5 across a range of important health outcomes and diseases supports policy measures to control PM2.5 concentrations. However, reasons for heterogeneity in effect estimates in different regions of the world require further investigation. Small study bias should also be considered in assessing and quantifying health risks from PM2.5.
AU  - Atkinson,R
AU  - Kang,S
AU  - Anderson,R
AU  - Mills,I
AU  - Walton,H
DO  - 10.1136/thoraxjnl-2013-204492
EP  - 665
PY  - 2014///
SN  - 0040-6376
SP  - 660
TI  - Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions: a systematic review and meta-analysis
T2  - a systematic review and meta-analysis
UR  - http://dx.doi.org/10.1136/thoraxjnl-2013-204492
UR  - https://thorax.bmj.com/content/69/7/660
UR  - http://hdl.handle.net/10044/1/61133
VL  - 69
ER  -
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