Imperial College London
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ProfessorHelenWard

Faculty of Medicine, School of Public Health

Professor of Public Health
 
 
 
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Contact

 

+44 (0)20 7594 3303h.ward Website

 
 
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Location

 

311School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Piggin:2022:10.1016/j.epidem.2022.100626,
author = {Piggin, M and Smith, E and Mankone, P and Ndegwa, L and Gbesemete, D and Pristera, P and Bahrami-Hessari, M and Johnson, H and Catchpole, AP and Openshaw, PJM and Chiu, C and Read, RC and Ward, H and Barker, C},
doi = {10.1016/j.epidem.2022.100626},
journal = {Epidemics: the journal of infectious disease dynamics},
pages = {1--6},
title = {The role of public involvement in the design of the first SARS-CoV-2 human challenge study during an evolving pandemic},
url = {http://dx.doi.org/10.1016/j.epidem.2022.100626},
volume = {41},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - High quality health care research must involve patients and the public. This ensures research is important, relevant and acceptable to those it is designed to benefit. The world’s first human challenge study with SARS-CoV-2 undertook detailed public involvement to inform study design despite the urgency to review and establish the study. The work was integral to the UK Research Ethics Committee review and approval of the study. Discussion with individuals from ethnic minorities within the UK population supported decision-making around the study exclusion criteria. Public review of study materials for consent processes led to the addition of new information, comparisons and visual aids to help volunteers consider the practicalities and risks involved in participating. A discussion exploring the acceptability of a human challenge study with SARS-CoV-2 taking place in the UK, given the current context of the pandemic, identified overall support for the study. Public concern for the wellbeing of trial participants, as a consequence of isolation, was identified. We outline our approach to public involvement and its impact on study design.
AU  - Piggin,M
AU  - Smith,E
AU  - Mankone,P
AU  - Ndegwa,L
AU  - Gbesemete,D
AU  - Pristera,P
AU  - Bahrami-Hessari,M
AU  - Johnson,H
AU  - Catchpole,AP
AU  - Openshaw,PJM
AU  - Chiu,C
AU  - Read,RC
AU  - Ward,H
AU  - Barker,C
DO  - 10.1016/j.epidem.2022.100626
EP  - 6
PY  - 2022///
SN  - 1755-4365
SP  - 1
TI  - The role of public involvement in the design of the first SARS-CoV-2 human challenge study during an evolving pandemic
T2  - Epidemics: the journal of infectious disease dynamics
UR  - http://dx.doi.org/10.1016/j.epidem.2022.100626
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000862280500002&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.sciencedirect.com/science/article/pii/S1755436522000664?via%3Dihub
UR  - http://hdl.handle.net/10044/1/101574
VL  - 41
ER  -
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