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@article{Atchison:2023:10.1136/archdischild-2022-325152,
author = {Atchison, C and Whitaker, M and Donnelly, C and Chadeau-Hyam, M and Riley, S and Darzi, A and Ashby, D and Barclay, W and Cooke, G and Elliott, P and Ward, H},
doi = {10.1136/archdischild-2022-325152},
journal = {Archives of Disease in Childhood},
title = {Characteristics and predictors of persistent symptoms post COVID-19 in children and young people: a large community cross-sectional study in England},
url = {http://dx.doi.org/10.1136/archdischild-2022-325152},
volume = {108},
year = {2023}
}

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TY  - JOUR
AB  - Objective: To estimate the prevalence of, and associated risk factors for, persistent symptoms post-COVID-19 among children aged 5–17 years in England.Design: Serial cross-sectional study.Setting: Rounds 10–19 (March 2021 to March 2022) of the REal-time Assessment of Community Transmission-1 study (monthly cross-sectional surveys of random samples of the population in England).Study population: Children aged 5–17 years in the community.Predictors: Age, sex, ethnicity, presence of a pre-existing health condition, index of multiple deprivation, COVID-19 vaccination status and dominant UK circulating SARS-CoV-2 variant at time of symptom onset.Main outcome measures: Prevalence of persistent symptoms, reported as those lasting ≥3 months post-COVID-19.Results: Overall, 4.4% (95% CI 3.7 to 5.1) of 3173 5–11 year-olds and 13.3% (95% CI 12.5 to 14.1) of 6886 12–17 year-olds with prior symptomatic infection reported at least one symptom lasting ≥3 months post-COVID-19, of whom 13.5% (95% CI 8.4 to 20.9) and 10.9% (95% CI 9.0 to 13.2), respectively, reported their ability to carry out day-to-day activities was reduced ‘a lot’ due to their symptoms. The most common symptoms among participants with persistent symptoms were persistent coughing (27.4%) and headaches (25.4%) in children aged 5–11 years and loss or change of sense of smell (52.2%) and taste (40.7%) in participants aged 12–17 years. Higher age and having a pre-existing health condition were associated with higher odds of reporting persistent symptoms.Conclusions: One in 23 5–11 year-olds and one in eight 12–17 year-olds post-COVID-19 report persistent symptoms lasting ≥3 months, of which one in nine report a large impact on performing day-to-day activities.
AU  - Atchison,C
AU  - Whitaker,M
AU  - Donnelly,C
AU  - Chadeau-Hyam,M
AU  - Riley,S
AU  - Darzi,A
AU  - Ashby,D
AU  - Barclay,W
AU  - Cooke,G
AU  - Elliott,P
AU  - Ward,H
DO  - 10.1136/archdischild-2022-325152
PY  - 2023///
SN  - 0003-9888
TI  - Characteristics and predictors of persistent symptoms post COVID-19 in children and young people: a large community cross-sectional study in England
T2  - Archives of Disease in Childhood
UR  - http://dx.doi.org/10.1136/archdischild-2022-325152
UR  - http://hdl.handle.net/10044/1/102775
VL  - 108
ER  -

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