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@article{Koshy:2015:10.1136/bmjopen-2014-006686,
author = {Koshy, E and Watt, H and Curcin, V and Bottle, A and Sharland, M and Saxena, S},
doi = {10.1136/bmjopen-2014-006686},
journal = {BMJ Open},
title = {Tonsillectomy among children with low baseline acute throat infection consultation rates in UK general practices: a cohort study},
url = {http://dx.doi.org/10.1136/bmjopen-2014-006686},
volume = {5},
year = {2015}
}

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TY  - JOUR
AB  - Objective: To investigate the effectiveness oftonsillectomy in reducing acute throat infection (ATI)consultation rates over 6 years’ follow-up amongchildren with low baseline ATI consultation rates.Design: Retrospective cohort study.Setting: UK general practices from the ClinicalPractice Research Datalink.Participants: Children aged 4–15 years with ≤3 ATIconsultations during the 3 years prior to 2001(baseline). 450 children who underwent tonsillectomy(tonsillectomy group) and 13 442 other children withan ATI consultation (comparison group) in 2001.Main outcome measures: Mean differences in ATIconsultation rates over the first 3 years’ andsubsequent 3 years’ follow-up compared with 3 yearsprior to 2001 (baseline); odds of ≥3 ATI consultationsat the same time points.Results: Among children in the tonsillectomy group,the 3-year mean ATI consultation rate decreased from1.31 to 0.66 over the first 3 years’ follow-up andfurther declined to 0.60 over the subsequent 3 years’follow-up period. Compared with children who had nooperation, those who underwent tonsillectomyexperienced a reduction in 3-year mean ATIconsultations per child of 2.5 (95% CI 2.3 to 2.6,p<0.001) over the first 3 years’ follow-up, but only 1.2(95% CI 1.0 to 1.4, p<0.001) over the subsequent3 years’ follow-up compared with baseline,respectively. This equates to a mean reduction of 3.7ATI consultations over a 6-year period andapproximates to a mean annual reduction of 0.6 ATIconsultations per child, per year, over 6 years’ followup.Children who underwent tonsillectomy were alsomuch less likely to experience ≥3 ATI consultationsduring the first 3 years’ follow-up (adjusted OR=0.12,95% CI 0.08 to 0.17) and the subsequent 3 years’follow-up (adjusted OR=0.24, 95% CI 0.14 to 0.41).Conclusions: Among children with low baseline ATIrates, there was a statistically significant reduction inATI consultation rates over 6 years’ foll
AU  - Koshy,E
AU  - Watt,H
AU  - Curcin,V
AU  - Bottle,A
AU  - Sharland,M
AU  - Saxena,S
DO  - 10.1136/bmjopen-2014-006686
PY  - 2015///
SN  - 2044-6055
TI  - Tonsillectomy among children with low baseline acute throat infection consultation rates in UK general practices: a cohort study
T2  - BMJ Open
UR  - http://dx.doi.org/10.1136/bmjopen-2014-006686
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000348774900006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/49461
VL  - 5
ER  -

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Hilary Watt CStat FHEA MSc MA(Oxon) BA

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