Imperial College London

Dr Haonan Lu

Faculty of MedicineDepartment of Surgery & Cancer

Research Assistant
 
 
 
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Contact

 

haonan.lu12

 
 
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Location

 

ICTEM buildingHammersmith Campus

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Summary

 

Summary

Cancer is a heterogeneous disease, meaning every tumour may addict to distinct oncogenic mechanisms and therefore need personalised treatment. This complexity could arise from genomic alterations (e.g. mutations), microenvironment changes (e.g. immune cells) and their interactions. Nevertheless, current therapeutic development mainly focuses on one of these alterations, resulting poor response in many cases.

Dr Haonan Lu was previously trained in bioinformatics and cell biology at Imperial College London. He is particularly interested in developing imaging-based methods to describe cancer phenotypes, as well as discovering novel therapeutic targets through functional genomics approach.

Publications

Journals

Aboagye E, Li Y, Inglese M, et al., 2021, Consideration of metabolite efflux in radiolabelled choline kinetics, Pharmaceutics, ISSN:1999-4923

Aboagye E, Wang N, Brickute D, et al., 2021, Novel non-congeneric derivatives of the choline kinase alpha inhibitor ICL-CCIC-0019, Pharmaceutics, Vol:13, ISSN:1999-4923, Pages:1-17

Lu H, Cunnea P, Nixon K, et al., 2021, Discovery of a biomarker candidate for surgical stratification in high-grade serous ovarian cancer, British Journal of Cancer, Vol:124, ISSN:0007-0920, Pages:1286-1293

Antonowicz S, Bodai Z, Wiggins T, et al., 2021, Endogenous aldehyde accumulation generates genotoxicity and exhaled biomarkers in esophageal adenocarcinoma, Nature Communications, Vol:12, ISSN:2041-1723

Hu Z, Cunnea P, Zhong Z, et al., 2021, The Oxford Classic links epithelial-to-mesenchymal transition to immunosuppression in poor prognosis ovarian cancers, Clinical Cancer Research, Vol:27, ISSN:1078-0432, Pages:1570-1579

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