Imperial College London
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MissHayleyThompson

Faculty of Medicine, School of Public Health

Casual - Academic Research
 
 
 
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hayley.thompson12

 
 
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Location

 

VA5Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ragonnet-Cronin:2021:10.1038/s41467-021-22366-y,
author = {Ragonnet-Cronin, M and Boyd, O and Geidelberg, L and Jorgensen, D and Nascimento, F and Siveroni, I and Johnson, R and Baguelin, M and Cucunuba, Z and Jauneikaite, E and Mishra, S and Watson, O and Ferguson, N and Cori, A and Donnelly, C and Volz, E},
doi = {10.1038/s41467-021-22366-y},
journal = {Nature Communications},
pages = {1--7},
title = {Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventions},
url = {http://dx.doi.org/10.1038/s41467-021-22366-y},
volume = {12},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Unprecedented public health interventions including travel restrictions and national lockdowns  have been implemented to stem the COVID-19 epidemic, but the effectiveness of non- pharmaceutical interventions is still debated.  We carried out a phylogenetic analysis of more than 29,000 publicly available whole genome  SARS-CoV-2 sequences from 57 locations to estimate the time that the epidemic originated in  different places. These estimates were examined in relation to the dates of the most stringent  interventions in each location as well as to the number of cumulative COVID-19 deaths and  phylodynamic estimates of epidemic size.   Here we report that the time elapsed between epidemic origin and maximum intervention is associated with different measures of epidemic severity and explains 11% of the variance in reported deaths one month after the most stringent intervention.   Locations where strong non-pharmaceutical interventions were implemented earlier experienced 30 much less severe COVID-19 morbidity and mortality during the period of study.
AU  - Ragonnet-Cronin,M
AU  - Boyd,O
AU  - Geidelberg,L
AU  - Jorgensen,D
AU  - Nascimento,F
AU  - Siveroni,I
AU  - Johnson,R
AU  - Baguelin,M
AU  - Cucunuba,Z
AU  - Jauneikaite,E
AU  - Mishra,S
AU  - Watson,O
AU  - Ferguson,N
AU  - Cori,A
AU  - Donnelly,C
AU  - Volz,E
DO  - 10.1038/s41467-021-22366-y
EP  - 7
PY  - 2021///
SN  - 2041-1723
SP  - 1
TI  - Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventions
T2  - Nature Communications
UR  - http://dx.doi.org/10.1038/s41467-021-22366-y
UR  - https://www.nature.com/articles/s41467-021-22366-y
UR  - http://hdl.handle.net/10044/1/86570
VL  - 12
ER  -
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