Publications

BibTex format

@article{Jameson:2015:10.1016/j.tet.2015.09.014,
author = {Jameson, VJA and Cocheme, HM and Logan, A and Hanton, LR and Smith, RAJ and Murphy, MP},
doi = {10.1016/j.tet.2015.09.014},
journal = {Tetrahedron},
pages = {8444--8453},
title = {Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants},
url = {http://dx.doi.org/10.1016/j.tet.2015.09.014},
volume = {71},
year = {2015}
}

Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - A series of mitochondria-targeted antioxidants comprising a lipophilic triphenylphosphonium cation attached to the antioxidant chroman moiety of vitamin E by an alkyl linker have been prepared. The synthesis of a series of mitochondria-targeted vitamin E derivatives with a range of alkyl linkers gave compounds of different hydrophobicities. This work will enable the dependence of antioxidant defence on hydrophobicity to be determined in vivo.
AU  - Jameson,VJA
AU  - Cocheme,HM
AU  - Logan,A
AU  - Hanton,LR
AU  - Smith,RAJ
AU  - Murphy,MP
DO  - 10.1016/j.tet.2015.09.014
EP  - 8453
PY  - 2015///
SN  - 1464-5416
SP  - 8444
TI  - Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants
T2  - Tetrahedron
UR  - http://dx.doi.org/10.1016/j.tet.2015.09.014
UR  - http://hdl.handle.net/10044/1/31377
VL  - 71
ER  -

Download

DrHelenaCocheme

Contact

Location

Summary

Citation

BibTex format

RIS format (EndNote, RefMan)