Summary
Imperial College Research Fellow interested in Cancer Regulatory Genomics (see Research for more details). MSc projects available to students in any quantitative biology discipline, and to students in computer science with a strong interest in Genomics.
Selected Publications
Journal Articles
Gorkin DU, Barozzi I, Zhao Y, et al. , 2020, An atlas of dynamic chromatin landscapes in mouse fetal development, Nature, Vol:583, ISSN:0028-0836, Pages:744-751
Hong SP, Lombardo Y, Chan TE, et al. , 2019, Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy, Nature Communications, Vol:10, ISSN:2041-1723
Comoglio F, Simonatto M, Polletti S, et al. , 2019, Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells, Genes & Development, Vol:33, ISSN:0890-9369, Pages:1159-1174
Oz-Levi D, Olender T, Bar-Joseph I, et al. , 2019, Noncoding deletions reveal a gene that is critical for intestinal function, Nature, Vol:571, ISSN:0028-0836, Pages:107-111
Osterwalder M, Barozzi I, Tissières V, et al. , 2018, Enhancer redundancy provides phenotypic robustness in mammalian development, Nature, Vol:554, ISSN:0028-0836, Pages:239-243
Monti R, Barozzi I, Osterwalder M, et al. , 2017, Limb-enhancer genie: an accessible resource of accurate enhancer predictions in the developing limb, PLOS Computational Biology, Vol:13, ISSN:1553-734X
Sheth R, Barozzi I, Langlais D, et al. , 2016, Distal limb patterning requires modulation of cis -regulatory activities by HOX13, Cell Reports, Vol:17, ISSN:2211-1247, Pages:2913-2926
Nguyen VTM, Barozzi I, Faronato M, et al. , 2015, Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion, Nature Communications, Vol:6, ISSN:2041-1723, Pages:1-15
Austenaa LMI, Barozzi I, Simonatto M, et al. , 2015, Transcription of mammalian cis-regulatory elements is restrained by actively enforced early termination, Molecular Cell, Vol:60, ISSN:1097-2765, Pages:460-474
Barozzi I, Simonatto M, Bonifacio S, et al. , 2014, Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers, Molecular Cell, Vol:54, ISSN:1097-2765, Pages:844-857
Ostuni R, Piccolo V, Barozzi I, et al. , 2013, Latent Enhancers Activated by Stimulation in Differentiated Cells, Cell, Vol:152, ISSN:0092-8674, Pages:157-171
De Santa F, Barozzi I, Mietton F, et al. , 2010, A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers, Plos Biology, Vol:8, Pages:e1000384-e1000384
Ghisletti S, Barozzi I, Mietton F, et al. , 2010, Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages, Immunity, Vol:32, ISSN:1074-7613, Pages:317-328