Imperial College London
Alternate

DrIsabelGarcia Perez

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Senior Lecturer in Precision and Systems Medicine
 
 
 
//

Contact

 

i.garcia-perez

 
 
//

Location

 

101Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Ismael:2013:10.1002/elps.201300066,
author = {Ismael, NA and Posma, JM and Frost, G and Holmes, E and Garcia-Perez, I},
doi = {10.1002/elps.201300066},
journal = {Electrophoresis},
pages = {2776--2786},
title = {The role of metabonomics as a tool for augmenting nutritional information in epidemiological studies},
url = {http://dx.doi.org/10.1002/elps.201300066},
volume = {34},
year = {2013}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Most chronic diseases have been demonstrated to have a link to nutrition. Within food and nutritional research there is a major driver to understand the relationship between diet and disease in order to improve health of individuals. However, the lack of accurate dietary intake assessment in free-living populations, makes accurate estimation of how diet is associated with disease risk difficult. Thus, there is a pressing need to find solutions to the inaccuracy of dietary reporting.Metabolic profiling of urine or plasma can provide an unbiased approach to characterizing dietary intake and various high throughput analytical platforms have been used in order to implement targeted and non-targeted assays in nutritional clinical trials and nutritional epidemiology studies.This review describes firstly the challenges presented in interpreting the relationship between diet and health within individual and epidemiological frameworks. Secondly we aim to explore how metabonomics can benefict different types of nutritional studies and discuss the critical importance of selecting appropriate analytical techniques in these studies. Thirdly we propose a strategy capable of providing accurate assessment of food intake within an epidemioligical framework in order establish accurate associations between diet and health.
AU  - Ismael,NA
AU  - Posma,JM
AU  - Frost,G
AU  - Holmes,E
AU  - Garcia-Perez,I
DO  - 10.1002/elps.201300066
EP  - 2786
PY  - 2013///
SP  - 2776
TI  - The role of metabonomics as a tool for augmenting nutritional information in epidemiological studies
T2  - Electrophoresis
UR  - http://dx.doi.org/10.1002/elps.201300066
VL  - 34
ER  -
Download