Imperial College London
Alternate

DrIanGodsland

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Wynn Reader in Human Metabolism
 
 
 
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Contact

 

+44 (0)20 3312 6573i.godsland

 
 
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Assistant

 

Mrs Heather Bones +44 (0)20 7594 2429

 
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Location

 

Room G1Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Raghavan:2018,
author = {Raghavan, A and Nanditha, A and Snehalatha, C and Vinitha, R and Susairaj, P and Simon, M and Selvam, S and Satheesh, K and Ram, J and Kumar, APN and Godsland, IF and Oliver, N and Johnston, DG and Ramachandran, A},
journal = {J Assoc Physicians India},
pages = {22--26},
title = {Incidence of Type 2 Diabetes is Higher among Men with Persistent Impaired Glucose Tolerance than in Transient Impaired Glucose Tolerance - A 5 year Follow up Study.},
url = {https://www.ncbi.nlm.nih.gov/pubmed/31317702},
volume = {66},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objective: This was a 5 year comparative analysis of the incidence of type 2 diabetes in men who had persistent impaired glucose tolerance (P-IGT) versus transient impaired glucose tolerance (T-IGT). P-IGT (positive IGT on two oral glucose tolerance tests (OGTT), T-IGT (IGT in first OGTT and normal glucose tolerance (NGT) in the 2nd OGTT). Methods: The samples were collected from a randomized controlled diabetes prevention study. The prevention study was done using lifestyle modification (LSM) promoted by use of mobile short message services (SMS) for 2 years. The control group of the randomized study who received advice on LSM at only the baseline formed the P-IGT group for the 3 years follow up study (n=236). T-IGT (n=569) were available from those who had NGT on the 2nd OGTT while screening for the prevention study. The total diabetes incidence at 5 years in the study groups were compared using standard OGTT (WHO criteria). Results: The conversion rate to diabetes in 5 years was significantly lower among T-IGT than among P-IGT, OR=0.202 (95% CI, 0.145-0.296,p< 0.0001). P-IGT had higher rate of risk factors for diabetes than T-IGT. Conclusion: The risk of conversion to diabetes was 80 percent lower in T-IGT than in P-IGT. Identification of P-IGT will help in selecting persons who require early intervention for diabetes.
AU  - Raghavan,A
AU  - Nanditha,A
AU  - Snehalatha,C
AU  - Vinitha,R
AU  - Susairaj,P
AU  - Simon,M
AU  - Selvam,S
AU  - Satheesh,K
AU  - Ram,J
AU  - Kumar,APN
AU  - Godsland,IF
AU  - Oliver,N
AU  - Johnston,DG
AU  - Ramachandran,A
EP  - 26
PY  - 2018///
SN  - 0004-5772
SP  - 22
TI  - Incidence of Type 2 Diabetes is Higher among Men with Persistent Impaired Glucose Tolerance than in Transient Impaired Glucose Tolerance - A 5 year Follow up Study.
T2  - J Assoc Physicians India
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31317702
VL  - 66
ER  -
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