Imperial College London

ProfessorIanGould

Faculty of Natural SciencesDepartment of Chemistry

Senior Research Investigator
 
 
 
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Contact

 

+44 (0)20 7594 5809i.gould

 
 
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Location

 

110BMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Dent:2016:10.1039/c6cc05954f,
author = {Dent, MR and López-Duarte, I and Dickson, CJ and Chairatana, P and Anderson, HL and Gould, IR and Wylie, D and Vyniauskas, A and Brooks, NJ and Kuimova, MK},
doi = {10.1039/c6cc05954f},
journal = {Chemical Communications},
pages = {13269--13272},
title = {Imaging plasma membrane phase behaviour in live cells using a thiophene-based molecular rotor},
url = {http://dx.doi.org/10.1039/c6cc05954f},
volume = {52},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Molecular rotors have emerged as versatile probes of microscopic viscosity in lipid bilayers, although it has proved difficult to find probes that stain both phases equally in phase-separated bilayers. Here, we investigate the use of a membrane-targeting viscosity-sensitive fluorophore based on a thiophene moiety with equal affinity for ordered and disordered lipid domains to probe ordering and viscosity within artificial lipid bilayers and live cell plasma membranes.
AU - Dent,MR
AU - López-Duarte,I
AU - Dickson,CJ
AU - Chairatana,P
AU - Anderson,HL
AU - Gould,IR
AU - Wylie,D
AU - Vyniauskas,A
AU - Brooks,NJ
AU - Kuimova,MK
DO - 10.1039/c6cc05954f
EP - 13272
PY - 2016///
SN - 1364-548X
SP - 13269
TI - Imaging plasma membrane phase behaviour in live cells using a thiophene-based molecular rotor
T2 - Chemical Communications
UR - http://dx.doi.org/10.1039/c6cc05954f
UR - http://hdl.handle.net/10044/1/42061
VL - 52
ER -