Imperial College London
Portrait Picture

ProfessorIolyKotta-Loizou

Faculty of Natural Sciences, Department of Life Sciences

Honorary Lecturer
 
 
 
//

Contact

 

i.kotta-loizou13

 
 
//

Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Filippou:2018:10.3390/v10120665,
author = {Filippou, C and Garrido-Jurado, I and Meyling, NV and Quesada-Moraga, E and Coutts, RHA and Kotta-Loizou, I},
doi = {10.3390/v10120665},
journal = {Viruses},
title = {Mycoviral population dynamics in Spanish isolates of the entomopathogenic fungus Beauveria bassiana},
url = {http://dx.doi.org/10.3390/v10120665},
volume = {10},
year = {2018}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The use of mycoviruses to manipulate the virulence of entomopathogenic fungi employed as biocontrol agents may lead to the development of novel methods to control attacks by insect pests. Such approaches are urgently required, as existing agrochemicals are being withdrawn from the market due to environmental and health concerns. The aim of this work is to investigate the presence and diversity of mycoviruses in large panels of entomopathogenic fungi, mostly from Spain and Denmark. In total, 151 isolates belonging to the genera Beauveria, Metarhizium, Lecanicillium, Purpureocillium, Isaria, and Paecilomyces were screened for the presence of dsRNA elements and 12 Spanish B. bassiana isolates were found to harbor mycoviruses. All identified mycoviruses belong to three previously characterised species, the officially recognised Beauveria bassiana victorivirus 1 (BbVV-1) and the proposed Beauveria bassiana partitivirus 2 (BbPV-2) and Beauveria bassiana polymycovirus 1 (BbPmV-1); individual B. bassiana isolates may harbor up to three of these mycoviruses. Notably, these mycovirus species are under distinct selection pressures, while recombination of viral genomes increases population diversity. Phylogenetic analysis of the RNA-dependent RNA polymerase gene sequences revealed that the current population structure in Spain is potentially a result of both vertical and horizontal mycovirus transmission. Finally, pathogenicity experiments using the Mediterranean fruit fly Ceratitis capitata showed no direct correlation between the presence of any particular mycovirus and the virulence of the B. bassiana isolates, but illustrated potentially interesting isolates that exhibit relatively high virulence, which will be used in more detailed virulence experimentation in the future.
AU  - Filippou,C
AU  - Garrido-Jurado,I
AU  - Meyling,NV
AU  - Quesada-Moraga,E
AU  - Coutts,RHA
AU  - Kotta-Loizou,I
DO  - 10.3390/v10120665
PY  - 2018///
SN  - 1999-4915
TI  - Mycoviral population dynamics in Spanish isolates of the entomopathogenic fungus Beauveria bassiana
T2  - Viruses
UR  - http://dx.doi.org/10.3390/v10120665
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000455313100004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.mdpi.com/1999-4915/10/12/665
UR  - http://hdl.handle.net/10044/1/108845
VL  - 10
ER  -
Download