Imperial College London
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ProfessorIolyKotta-Loizou

Faculty of Natural Sciences, Department of Life Sciences

Honorary Lecturer
 
 
 
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Contact

 

i.kotta-loizou13

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Zhou:2021:10.1038/s41396-021-00892-3,
author = {Zhou, L and Li, X and Kotta-Loizou, I and Dong, K and Li, S and Ni, D and Hong, N and Wang, G and Xu, W},
doi = {10.1038/s41396-021-00892-3},
journal = {The ISME Journal: multidisciplinary journal of microbial ecology},
pages = {1893--1906},
title = {A mycovirus modulates the endophytic and pathogenic traits of a plant associated fungus},
url = {http://dx.doi.org/10.1038/s41396-021-00892-3},
volume = {15},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Fungi are generally thought to live in host plants with a single lifestyle, being parasitism, commensalism, or mutualism. The former, known as phytopathogenic fungi, cause various plant diseases that result in significant losses every year; while the latter, such as endophytic fungi, can confer fitness to the host plants. It is unclear whether biological factors can modulate the parasitic and mutualistic traits of a fungus. In this study, we isolated and characterized a mycovirus from an endophytic strain of the fungus Pestalotiopsis theae, a pathogen of tea (Camellia sinensis). Based on molecular analysis, we tentatively designated the mycovirus as Pestalotiopsis theae chrysovirus-1 (PtCV1), a novel member of the family Chrysoviridae, genus Alphachrysovirus. PtCV1 has four double-stranded (ds) RNAs as its genome, ranging from 0.9 to 3.4 kbp in size, encapsidated in isometric particles. PtCV1 significantly reduced the growth rates of its host fungus in vitro (ANOVA; P-value < 0.001) and abolished its virulence in planta (ANOVA; P-value < 0.001), converting its host fungus to a non-pathogenic endophyte on tea leaves, while PtCV1-free isolates were highly virulent. Moreover, the presence of PtCV1 conferred high resistance to the host plants against the virulent P. theae strains. Here we report a mycovirus that modulates endophytic and phytopathogenic fungal traits and provides an alternative approach to biological control of plant diseases caused by fungi.
AU  - Zhou,L
AU  - Li,X
AU  - Kotta-Loizou,I
AU  - Dong,K
AU  - Li,S
AU  - Ni,D
AU  - Hong,N
AU  - Wang,G
AU  - Xu,W
DO  - 10.1038/s41396-021-00892-3
EP  - 1906
PY  - 2021///
SN  - 1751-7362
SP  - 1893
TI  - A mycovirus modulates the endophytic and pathogenic traits of a plant associated fungus
T2  - The ISME Journal: multidisciplinary journal of microbial ecology
UR  - http://dx.doi.org/10.1038/s41396-021-00892-3
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000613979200001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://www.nature.com/articles/s41396-021-00892-3
UR  - http://hdl.handle.net/10044/1/87560
VL  - 15
ER  -
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