Publications
119 results found
Richards SK, Parton LE, Leclerc I, et al., 2005, Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function <i>in vivo</i>, JOURNAL OF ENDOCRINOLOGY, Vol: 187, Pages: 225-235, ISSN: 0022-0795
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- Citations: 79
Richards SK, LeClerc I, Mathieson PW, et al., 2005, The effect of AMP-activated protein kinase on success rate and glycaemic control of murine islet isografts, Annual Meeting of the Association-of-Surgeons-of-Great-Britian-and-Ireland, Publisher: JOHN WILEY & SONS LTD, Pages: 34-34, ISSN: 0007-1323
Richards SK, Parton LE, Leclerc I, et al., 2005, AMP-activated protein kinase (AMPK) activity in murine islet isografts as a determinant of recipient glycaemic control, 65th Annual Meeting of the American-Diabetes-Association, Publisher: AMER DIABETES ASSOC, Pages: A480-A480, ISSN: 0012-1797
Rutter GA, Richards SK, Parton LE, et al., 2005, Over-expression of activated AMP-activated protein kinase (AMPK) impairs in vivo pancreatic β-cell function in transplanted pancreatic islets, 41st Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Publisher: SPRINGER, Pages: A88-A88, ISSN: 0012-186X
Xavier GD, Diraison F, Qian Q, et al., 2005, Carbohydrate response-element binding protein regulates liver-type pyruvate kinase and pancreatic duodenum homeobox-1 expression in MIN6 β-cells by direct and indirect mechanisms, respectively, 41st Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Publisher: SPRINGER, Pages: A157-A157, ISSN: 0012-186X
Diraison F, Motakis E, Parton LE, et al., 2004, Impact of adenoviral transduction with SREBP1c or AMPK on pancreatic islet gene expression profile - Analysis with oligonucleotide microarrays, DIABETES, Vol: 53, Pages: S84-S91, ISSN: 0012-1797
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- Citations: 28
Leclerc I, Rutter GA, 2004, AMP-activated protein kinase:: A new β-cell glucose sensor?: Regulation by amino acids and calcium ions, DIABETES, Vol: 53, Pages: S67-S74, ISSN: 0012-1797
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- Citations: 74
Rutter GA, Ma D, Shield JPH, et al., 2004, Altered glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus (TNDM) locus, 40th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Publisher: SPRINGER, Pages: A53-A54, ISSN: 0012-186X
Diraison F, Xavier GD, Motakis E, et al., 2004, Impact of over-expression of carbohydrate response-element binding-protein (ChREBP) on pancreatic beta-cell gene expression profile and insulin secretion, 40th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Publisher: SPRINGER, Pages: A162-A162, ISSN: 0012-186X
, 2004, 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004., Diabetologia, Vol: 47, Pages: A1-A464
Ma D, Shield JPH, Dean W, et al., 2004, Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, <i>TNDM</i>, JOURNAL OF CLINICAL INVESTIGATION, Vol: 114, Pages: 339-348, ISSN: 0021-9738
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- Citations: 124
Veitenhansl M, Stegner K, Hierl FX, et al., 2004, Special pre-manufactured footwear with insoles can prevent ulceration in diabetic patients with diabetic foot syndrome by pressure reduction. A prospective randomised study, 40th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Publisher: SPRINGER, Pages: A3-A3, ISSN: 0012-186X
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- Citations: 23
Rutter GA, Leclerc I, Tsuboi T, et al., 2004, Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet β-Cells: Control by AMP-Activated Protein Kinase, Cellular biochem and biophys review, Vol: 40, Pages: 179-190
Leclerc I, Woltersdorf WW, da Silva Xavier G, et al., 2004, Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion., Am J Physiol Endocrinol Metab, Vol: 286, Pages: E1023-E1031
Diraison F, Parton L, Ferré P, et al., 2004, Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release:: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), BIOCHEMICAL JOURNAL, Vol: 378, Pages: 769-778, ISSN: 0264-6021
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- Citations: 86
Rutter GA, Leclerc I, Tsuboi T, et al., 2004, Imaging glucose-regulated insulin secretion and gene expression in single islet β-cells -: Control by AMP-activated protein kinase, CELL BIOCHEMISTRY AND BIOPHYSICS, Pages: 179-190, ISSN: 1085-9195
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- Citations: 4
Tsuboi T, da Silva Xavier G, Leclerc I, et al., 2003, 5'-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics., J Biol Chem, Vol: 278, Pages: 52042-52051
Rutter GA, Da Silva Xavier G, 2003, Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis., Biochem J, Vol: 375, Pages: 1-16
da Silva Xavier G, Leclerc I, Varadi A, et al., 2003, Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression, Biochem J, Vol: 371, Pages: 761-774, ISSN: 0264-6021
Zhang P, Bennoun M, Gogard C, et al., 2002, Expression of COUP-TFII in metabolic tissues during development, MECHANISMS OF DEVELOPMENT, Vol: 119, Pages: 109-114, ISSN: 0925-4773
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- Citations: 30
Xavier GD, Leclerc I, Rutter GA, 2002, Glucose-regulated gene expression via inhibition of AMP-activated protein kinase and activated insulin secretion in MIN6 pancreatic β cells, DIABETES, Vol: 51, Pages: A2-A2, ISSN: 0012-1797
Bourdeau I, Bard C, Noël B, et al., 2002, Loss of brain volume in endogenous Cushing's syndrome and its reversibility after correction of hypercortisolism, JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, Vol: 87, Pages: 1949-1954, ISSN: 0021-972X
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- Citations: 167
Leclerc I, Viollet B, da Silva Xavier G, et al., 2002, Role of AMP-activated protein kinase in the regulation of gene transcription., Biochem Soc Trans, Vol: 30, Pages: 307-311, ISSN: 0300-5127
Leclerc I, da Silva Xavier G, Rutter GA, 2002, AMP- and stress-activated protein kinases: key regulators of glucose-dependent gene transcription in mammalian cells?, Prog Nucleic Acid Res Mol Biol., Vol: 71, Pages: 69-90
Leclerc I, Lenzner C, Gourdon L, et al., 2001, Hepatocyte nuclear factor-4α involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase, DIABETES, Vol: 50, Pages: 1515-1521, ISSN: 0012-1797
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- Citations: 134
da Silva Xavier G, Leclerc I, Rutter GA, et al., 2000, Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression., Proc Natl Acad Sci U S A., Vol: 97, Pages: 4023-4028
Freeman DJ, Leclerc I, Rutter GA, 1999, Present and potential future use of gene therapy for the treatment of non-insulin dependent diabetes mellitus (Review), INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol: 4, Pages: 585-592, ISSN: 1107-3756
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- Citations: 6
Leclerc I, Kahn A, Doiron B, 1998, The 5′-AMP-activated protein kinase inhibits the transcriptional stimulation by glucose in liver cells, acting through the glucose response complex, FEBS LETTERS, Vol: 431, Pages: 180-184, ISSN: 0014-5793
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- Citations: 127
LECLERC I, DAVIGNON I, LOPEZ D, et al., 1993, NO CHANGE IN GLUCOSE-TOLERANCE AND SUBSTRATE OXIDATION AFTER A HIGH-CARBOHYDRATE, LOW-FAT DIET, METABOLISM-CLINICAL AND EXPERIMENTAL, Vol: 42, Pages: 365-370, ISSN: 0026-0495
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- Citations: 11
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