Collaborators
Dhan V. Kalvakolanu, Ph.D., University of Maryland School of Medicine, ATF6 FRET sensor, 2017
Alejandra Tomas, Imperial College London, Electron microscopy of ER-mitochondria junctions pancreatic beta cells, 2016
Dr Catherine Postic, INSERM, ChREBP in the liver, 2015
Prof Fiona Gribble, University of Cambridge Metabolic Research Laboratories, Incretin biology, 2015
Richard O'Brien, Vanderbilt University, G6PC2 and sorcin, 2015
Prof Phillipp E. Scherer, PhD, The University of Texas Southwestern Medical Center, Adipose tissue specific rtTA transgenic mouse, 2015
Prof Hector Valdivia, University of Michigan, Sorcin, 2014
Guest Lectures
Sorcin links ER Ca2+ Stores to Beta Cell Lipotoxicity. Novel Islet Signaling Pathways Symposium., 77th Scientific Sessions, American Diabetes Association, San Diego, California, USA, 2017
Research Staff
Scott,F
Research Student Supervision
Ayathamattam,J, Generation and characterisation of Sri-/- MEF cell lines with regards to ER stress and ATF6 activity
Bellomo,E, Divalent metal ions in pancreatic beta-cell function: role in the pathogenesis of type 2 diabetes
Carmichael,L, The role of calcium sensor Sorcin in ER stress-induced apoptosis in pancreatic beta cells
Carmichael,L, The role of calcium sensor Sorcin in ER-stress-induced apoptosis in pancreatic beta cells
Gao,T, Is sorcin an ER stress marker
Hall,D, Exploration of sorcin’s therapeutic potential against lipoglucotoxicity in pancreatic β-cells
Jimenez Awuapara,N, Generation and characterisation of Sorcin knockout human embryonic kidney 293 cell line by CRISPR/Cas9: effects on endoplasmic reticulum stress and ATF6 activation
Kwieder,B, Investigating the roles of Pin1 in pancreatic islet beta cells
Mannan,N, Regulation of the G6PC2 promoter by glucose and sorcin in pancreatic beta cells
Parks,S, Investigating the role of sorcin in the development of ER stress-induced obesity and Type 2 diabetes
Patel,P, Investigating the interaction of ChREBP and sorcin in mammalian cell lines
Sun,G, Roles of AMP-activated protein kinase (AMPK) and liver kinase B1 (LKB1) in controlling pancreatic islet hormone secretion
Thepaut,C, The role of sorcin in pancreatic beta-cell viability and apoptosis
Wai,FS, Exploration of sorcin therapeutic potential against glucolipotoxicity in pancreatic beta cells