Imperial College London
Dr Ian Maconochie

DrIanMaconochie

Faculty of Medicine, Department of Infectious Disease

Professor of Practice (Paediatric Emergency Medicine)
 
 
 
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Contact

 

+44 (0)20 3312 3729i.maconochie

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Topjian:2021:10.1016/j.resuscitation.2021.01.023,
author = {Topjian, AA and Scholefield, BR and Pinto, NP and Fink, EL and Buysse, CMP and Haywood, K and Maconochie, I and Nadkarni, VM and de, Caen A and Escalante-Kanashiro, R and Ng, K-C and Nuthall, G and Reis, AG and Van, de Voorde P and Suskauer, SJ and Schexnayder, SM and Hazinski, MF and Slomine, BS},
doi = {10.1016/j.resuscitation.2021.01.023},
journal = {Resuscitation},
pages = {351--364},
title = {P-COSCA (Pediatric Core Outcome Set for Cardiac Arrest) in Children: An Advisory Statement From the International Liaison Committee on Resuscitation.},
url = {http://dx.doi.org/10.1016/j.resuscitation.2021.01.023},
volume = {162},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Studies of pediatric cardiac arrest use inconsistent outcomes, including return of spontaneous circulation and short-term survival, and basic assessments of functional and neurological status. In 2018, the International Liaison Committee on Resuscitation sponsored the COSCA initiative (Core Outcome Set After Cardiac Arrest) to improve consistency in reported outcomes of clinical trials of adult cardiac arrest survivors and supported this P-COSCA initiative (Pediatric COSCA). The P-COSCA Steering Committee generated a list of potential survival, life impact, and economic impact outcomes and assessment time points that were prioritized by a multidisciplinary group of healthcare providers, researchers, and parents/caregivers of children who survived cardiac arrest. Then expert panel discussions achieved consensus on the core outcomes, the methods to measure those core outcomes, and the timing of the measurements. The P-COSCA includes assessment of survival, brain function, cognitive function, physical function, and basic daily life skills. Survival and brain function are assessed at discharge or 30 days (or both if possible) and between 6 and 12 months after arrest. Cognitive function, physical function, and basic daily life skills are assessed between 6 and 12 months after cardiac arrest. Because many children have prearrest comorbidities, the P-COSCA also includes documentation of baseline (ie, prearrest) brain function and calculation of changes after cardiac arrest. Supplementary outcomes of survival, brain function, cognitive function, physical function, and basic daily life skills are assessed at 3 months and beyond 1 year after cardiac arrest if resources are available.
AU  - Topjian,AA
AU  - Scholefield,BR
AU  - Pinto,NP
AU  - Fink,EL
AU  - Buysse,CMP
AU  - Haywood,K
AU  - Maconochie,I
AU  - Nadkarni,VM
AU  - de,Caen A
AU  - Escalante-Kanashiro,R
AU  - Ng,K-C
AU  - Nuthall,G
AU  - Reis,AG
AU  - Van,de Voorde P
AU  - Suskauer,SJ
AU  - Schexnayder,SM
AU  - Hazinski,MF
AU  - Slomine,BS
DO  - 10.1016/j.resuscitation.2021.01.023
EP  - 364
PY  - 2021///
SP  - 351
TI  - P-COSCA (Pediatric Core Outcome Set for Cardiac Arrest) in Children: An Advisory Statement From the International Liaison Committee on Resuscitation.
T2  - Resuscitation
UR  - http://dx.doi.org/10.1016/j.resuscitation.2021.01.023
UR  - https://www.ncbi.nlm.nih.gov/pubmed/33515637
VL  - 162
ER  -
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