Publications
239 results found
Nagy I, Santha P, 2008, Insulin-induced effects on thermo-sensitive ion channels in cultured primary sensory neurons, Conference on Neuropeptide - Functions, Dysfunctions and Therapeutic Options, Publisher: CHURCHILL LIVINGSTONE, Pages: 470-471, ISSN: 0143-4179
Nagy I, White JPM, Paule CC, et al., 2008, An historical introduction to the endocannabinoid and endovanilloid systems, Cannabinoids and the Brain, Pages: 3-13, ISBN: 9780387743486
Cannabis and chili pepper have been used for medical, gastronomical and recreational purposes for at least 8,000 years. Nevertheless, it was discovered only eight years ago that the cloned neuronal targets of their active principles, delta9-tetrahydrocannabinol (Δ9-THC) and capsaicin are related to each other, as they all can be activated by some arachidonic acid-derivative endogenous ligands. Here, we will summarize the history of man's relationship with cannabis and capsaicin, and we will detail the most important scientific keystones in the evolution of cannabinoid and vanilloid research, featuring the list of cannabinoid and capsaicin effects, the discovery of endogenous ligands and the cloning of receptors, namely, the CB1 and the CB2 cannabinoid receptor as well as the TRPV1 vanilloid receptor, where the endogenous and the plant-derived substances act upon. This chapter serves, therefore, as an introduction to Cannabinoids and the Brain, the book which will extensively describe the neuronal and, to some extent, the peripheral cannabinoid and vanilloid systems in molecular, pharmacological, physiological, pathological and neuropsychiatric viewpoints.
Mistry S, Paule CC, Photiou A, et al., 2008, Inflammatory mediator-evoked transcriptional changes in the TRPV1 splice variant, TRPV1b, in cultured primary sensory neurons., Meeting of the Physiological Society
Charrua A, Reguenga C, Paule CC, et al., 2008, Cystitis is associated with TRPV1b-downregulation in rat dorsal root ganglia., Neuroreport, Vol: 19, Pages: 1469-1472
Charrua A, Reguenga C, Paule CC, et al., 2008, Down-regulation of the TRPV1b splice variant in dorsal root ganglia innervating the inflamed urinary bladder of the rat., Neuropeptides, Vol: 42
Paule CC, Davis J, Nagy I, 2008, Responses of human TRPV1 polymorphs, Annual Meeting of the European Neuropeptide Club
Nagy I, White JPM, Paule CC, et al., 2008, Cannabis, capsaicin and the history of their research, Cannabinoids and the Brain, Editors: Kofalvi, Publisher: Springer, Pages: 3-13
Cruz F, Charrua A, Reguenga C, et al., 2008, TRPV1 expression in human urothelial cells., Neuropeptides, Vol: 42, Pages: 469-470
Nagy I, 2008, Xenon reduces the activity of the transient receptor potential vanilloid type 1 ion channel, European Winter Conference on Brain Research
Nagy I, White JPM, Paule CC, et al., 2008, Functional Molecular Biology of the TRPV1 Ion Channel, Cannabinoids and the Brain, Editors: Kofalvi, Publisher: Springer, Pages: 101-130
Silva AA, Charrua A, Reguenga C, et al., 2008, Human urothelial cells respond to inflammatory mediators trough a TRPV1-dependent mechanism, Annual Meeting of the Society for Neuroscience
Cruz F, Charrua A, Reguenga C, et al., 2008, TRPV1 expression in human urothelial cells, Conference on Neuropeptide - Functions, Dysfunctions and Therapeutic Options
Paule CC, Davis JB, Nagy I, 2008, DMSO activates TRPV1., Neuropeptides, Vol: 42
Charrua A, Paule CC, Nagy I, et al., 2008, Down-regulation of the TRPV1b splice variant in dorsal root ganglia innervating the inflamed urinary bladder of the rat., Annual Meeting of the European Neuropeptide Club
Nagy I, 2008, The effect of cannabinoids on nociceptive primary sensory neurons, Euroanaesthesia
White J, Calcott G, Jenes A, et al., 2008, Xenon reduces responses mediated through the transient receptor potential vanilloid type 1 receptor (TRPV1), 12th World Congress of the International Association of Studying Pain
Mistry S, Paule CC, Photiou A, et al., 2008, Inflammatory mediator-evoked transcriptional changes in the TRPV1 splice variant, TRPV1b, in cultured primary sensory neurons., Proc Physiol Soc, Vol: 12
Paule CC, Davis JB, Nagy I, 2008, Human TRPV1 polymorphs show different sensitivity to various activators., Neuropeptides, Vol: 42
Paule CC, Davis J, Nagy I, 2008, DMSO activates TRPV1. Annual Meeting of the european Neuropeptide club, Conference on Neuropeptide - Functions, Dysfunctions and Therapeutic Options
Nagy I, 2008, Mechanisms activating the transient receptor potential vanilloid type 1 receptor (TRPV1) in the inflamed tissues, European Winter Conference on Brain Research
Nagy I, 2008, The effect of cannabinoids on nociceptive primary sensory neurons, 12th World Congress of the International Association of Studying Pain
Nagy I, Santha P, 2008, Insulin-induced effects on thermo-sensitive ion channels in cultured primary sensory neurons., Neuropeptides, Vol: 42
Nagy I, 2007, Mechanisms activating the transient receptor potential vanilloid type 1 receptor (trpv1) in the inflamed urinary bladder, World Institute of Pain
Paule CC, Davis JB, Nagy I, 2007, How hot are the Chilli Peppers?, World Institute of Pain
Baiou J, Santha P, Avelino A, et al., 2007, Neurochemical characterization of insulin receptor-expressing primary sensory neurons in wild-type and vanilloid type 1 transient receptor potential receptor knockout mice, World Institute of Pain
Baiou D, Santha P, Avelino A, et al., 2007, Neurochemical characterization of insulin receptor-expressing primary sensory neurons in wild-type and vanilloid type 1 transient receptor potential receptor knockout mice, JOURNAL OF COMPARATIVE NEUROLOGY, Vol: 503, Pages: 334-347, ISSN: 0021-9967
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- Citations: 34
Nagy I, Paule C, White J, et al., 2007, Taking the sting out of pain, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 151, Pages: 721-722, ISSN: 0007-1188
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- Citations: 2
Paule CC, Davis JB, Nagy I, 2007, Conference on Neuropeptide - Functions, Dysfunctions and Therapeutic Options, Conference on Neuropeptide - Functions, Dysfunctions and Therapeutic Options
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