Imperial College London

DrIsabelleSalles

Faculty of MedicineDepartment of Immunology and Inflammation

Honorary Lecturer
 
 
 
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Contact

 

+44 (0)20 3313 2298i.salles

 
 
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Location

 

5S5Commonwealth BuildingHammersmith Campus

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Summary

 

Summary

Isabelle Salles-Crawley graduated from Université Blaise Pascal in Clermont-Ferrand, France in 1995 with a MSc in Molecular and Plant Biology, and obtained her PhD in Microbiology from the University of Oklahoma in 2001. Her first post-doctoral position was at the University of Oklahoma in Professor Jimmy Ballard's laboratory, exploring the pathogenesis of bacterial toxins. In 2004, she joined the Thrombosis and Haemostasis group with Professors Hans Deckmyn and Karen Vanhoorelbeke at KU-Leuven, Belgium. She joined the Centre for Haematology at Imperial College London in 2009 where she received a BHF Intermediate Basic Science Research Fellowship to investigate the role of BAMBI in thrombus formation. Isabelle secured additional funding from the British Heart Foundation to continue her research at Imperial College and became an Advanced Research Fellow in 2020. She joined the Molecular and Clinical Sciences Research Institute at St George’s University of London as a Lecturer in Cardiovascular Science in September 2021 and is an Honorary Lecturer at Imperial College.

Over the years she has developed many in vitro and in vivo models of thrombosis and published over 35 papers in peer-reviewed scientific journals. She recently joined the editorial board of Research and Practice in Thrombosis and Haemostasis.

She is a committee member of the British Society for Thrombosis and Haemostasis, a member of the International Society on Thrombosis and Haemostasis and the Platelet Society.

 

Publications

Journals

Constantinescu-Bercu A, Wang YA, Woollard KJ, et al., 2022, The GPIbα intracellular tail – role in transducing VWF- and collagen/GPVI-mediated signaling, Haematologica, Vol:107, ISSN:0390-6078, Pages:933-946

Huang Y, Gu B, Salles II, et al., 2021, Fibrinogen-mimicking, multi-arm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy, Science Advances, Vol:7, ISSN:2375-2548

Salles-Crawley II, 2021, Targeting platelets to improve post-thrombotic syndrome?, Journal of Thrombosis and Haemostasis, Vol:19, ISSN:1538-7836, Pages:355-357

Constantinescu-Bercu A, Salles-Crawley II, Crawley JTB, 2020, SLC44A2-A novel therapeutic target for venous thrombosis?, Journal of Thrombosis and Haemostasis, Vol:18, ISSN:1538-7836, Pages:1556-1558

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