Dr Isabelle Salles is a British Heart Foundation Basic Science Research Fellow in the Haemostasis and Thrombosis group in the Centre for Haematology and works in collaboration with Professor David Lane and Dr Jim Crawley.
She graduated from Université Blaise Pascal in Clermont-Ferrand, France in 1995 with a MSc in Molecular and Plant Biology, and obtained her PhD in Microbiology from the University of Oklahoma in 2001. Her first post-doctoral position was at the University of Oklahoma in Professor Jimmy Ballard's laboratory, exploring the pathogenesis of bacterial toxins. In 2004, she joined the Thrombosis and Haemostasis group with Professors Hans Deckmyn and Karen Vanhoorelbeke at the KU-Leuven, Belgium. She joined the Centre for Haematology at Imperial College London in 2009. Her current research interests include platelet biology with particular attention to platelet receptors and how they affect platelet function and haemostasis and thrombosis.
et al., 2021, The GPIbα intracellular tail – role in transducing VWF- and collagen/GPVI-mediated signaling, Haematologica, ISSN:0390-6078
et al., 2021, Fibrinogen-mimicking, multi-arm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy, Science Advances, Vol:7, ISSN:2375-2548
Salles-Crawley II, 2021, Targeting platelets to improve post-thrombotic syndrome?, Journal of Thrombosis and Haemostasis, Vol:19, ISSN:1538-7836, Pages:355-357
Constantinescu-Bercu A, Salles-Crawley II, Crawley JTB, 2020, SLC44A2-A novel therapeutic target for venous thrombosis?, Journal of Thrombosis and Haemostasis, Vol:18, ISSN:1538-7836, Pages:1556-1558