Imperial College London
Alternate

DrInesRibeiro Violante

Faculty of Medicine, Department of Brain Sciences

Honorary Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 7994i.violante

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Araña-Oiarbide:2020:10.1101/2020.07.29.223180,
author = {Araña-Oiarbide, G and Daws, RE and Lorenz, R and Violante, IR and Hampshire, A},
doi = {10.1101/2020.07.29.223180},
title = {Preferential activation of the posterior Default-Mode Network with sequentially predictable task switches},
url = {http://dx.doi.org/10.1101/2020.07.29.223180},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:title>Abstract</jats:title><jats:p>The default-mode network (DMN) has been primarily associated with internally-directed and self-relevant cognition. This perspective is expanding to recognise its importance in executive behaviours like switching. We investigated the effect different task-switching manipulations have on DMN activation in two studies with novel fMRI paradigms. In the first study, the paradigm manipulated visual discriminability, visuo-perceptual distance and sequential predictability during switching. Increased posterior cingulate/precuneus (PCC/PrCC) activity was evident during switching; critically, this was strongest when the occurrence of the switch was predictable. In the second study, we sought to replicate and further investigate this switch-related effect with a fully factorial design manipulating sequential, spatial and visual-feature predictability. Whole-brain analysis again identified a PCC/PrCC-centred cluster that was more active for sequentially predictable versus unpredictable switches, but not for the other predictability dimensions. We propose PCC/PrCC DMN subregions may play a prominent executive role in mapping the sequential structure of complex tasks.</jats:p>
AU  - Araña-Oiarbide,G
AU  - Daws,RE
AU  - Lorenz,R
AU  - Violante,IR
AU  - Hampshire,A
DO  - 10.1101/2020.07.29.223180
PY  - 2020///
TI  - Preferential activation of the posterior Default-Mode Network with sequentially predictable task switches
UR  - http://dx.doi.org/10.1101/2020.07.29.223180
ER  -
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