Prof. Wilson holds the Chair in Drug Metabolism and Molecular Toxicology.
Ian Wilson trained as a biochemist at the University of Manchester Institute of Science and Technology, going on to a PhD at Keele University on insect moulting hormones. After this he worked in the Pharmaceutical industry, most recently as a Senior Principal Scientist in the Dept of Drug Metabolism and Pharmacokinetics at the AstraZeneca Research site at Alderley Park in Cheshire (UK), joining Imperial College in 2012. He is the author, or co-author, of some 480 papers or reviews, and has received a number of awards in separation and analytical science from the Royal Society of Chemistry, including the Gold Medal of the Analytical Division (2005) and most recently the Knox Medal of the RSC Separation Science Group (2012). He received the Jubilee Medal of the Chromatographic Society in 1994 and gave the inaugural Desty Memorial lecture for Innovation in Separation Science in1996. His research is directed towards the development of hyphenated techniques in chromatography and their application to problems in drug metabolism, toxicology and metabonomics
et al., 2020, UHPLC-MS-Based lipidomic and metabonomic investigation of the metabolic phenotypes of wild type and hepatic CYP reductase null (HRN) mice, Journal of Pharmaceutical and Biomedical Analysis, Vol:186, ISSN:0731-7085, Pages:1-9
et al., Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat, Chromatographia, ISSN:0009-5893
et al., 2020, Metabolism and effects on endogenous metabolism of paracetamol (acetaminophen) in a porcine model of liver failure, Toxicological Sciences, Vol:175, ISSN:1096-0929, Pages:87-97
et al., 2020, The analysis of acetaminophen (paracetamol) and 7 metabolites in rat, pig and human plasma by U(H)PLC-MS, Bioanalysis, Vol:12, ISSN:1757-6180, Pages:485-500
et al., 2020, Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships, Organic and Biomolecular Chemistry, Vol:18, ISSN:1477-0520, Pages:1389-1401