Publications
415 results found
Harrington LS, Mitchell JA, 2004, Novel role for P2X receptor activation in endothelium-dependent vasodilation, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 143, Pages: 611-617, ISSN: 0007-1188
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- Citations: 40
Osborne CS, Chakalova L, Brown KE, et al., 2004, Active genes dynamically colocalize to shared sites of ongoing transcription, NATURE GENETICS, Vol: 36, Pages: 1065-1071, ISSN: 1061-4036
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- Citations: 793
Warner TD, Vojnovic I, Giuliano F, et al., 2004, Cyclooxygenases 1, 2, and 3 and the production of prostaglandin I<sub>2</sub>:: Investigating the activities of acetaminophen and cyclooxygenase-2-selective inhibitors in rat tissues, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 310, Pages: 642-647, ISSN: 0022-3565
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- Citations: 38
Warner TD, Mitchell JA, 2004, Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic, FASEB JOURNAL, Vol: 18, Pages: 790-804, ISSN: 0892-6638
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- Citations: 462
Stanford SJ, Walters MJ, Mitchell JA, 2004, Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 486, Pages: 349-352, ISSN: 0014-2999
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- Citations: 28
Warner TD, Mitchell JA, 2003, HIF, stretching to get control of VEGF., Clin Sci (Lond), Vol: 105, Pages: 393-394, ISSN: 0143-5221
Mechanical forces are key regulators of cell function, particularly of cells within the arterial wall that are exposed to the shear stress and pulsatile pressure of flowing blood. The finding by Chang and colleagues in this issue of Clinical Science that cell stretch can up-regulate the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor, which is a key regulator of blood vessel remodelling, provides us with further insight into the mechanisms underlying remodelling at sites of occlusive disease within the cardiovascular system.
Woods M, Wood EG, Bardswell SC, et al., 2003, Role for nuclear factor-κB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells, MOLECULAR PHARMACOLOGY, Vol: 64, Pages: 923-931, ISSN: 0026-895X
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- Citations: 49
Stanford SJ, San H, Nabel EG, et al., 2003, Induction of heme oxygenase-1 in the murine lung afterbirth does not influence vascular remodelling, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Fleet MR, Anandarajah J, Walters MJ, et al., 2003, Cigarette smoke inhibits the induction of NOSII activity in murine macrophages stimulated with Gram negative bacteria, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Harrington LS, Mitchell JA, 2003, Activation of P2X-like receptors in rat isolated 2<SUP>nd</SUP> order mesenteric arteries induces vasodilation:: Role of EDHF, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Somuyiwa A, Stanford S, Gitlin J, et al., 2003, Cyclo-oxygenase-2 expression in the lung in the period of pulmonary development after birth, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Anandarajah J, Fleet MR, Walters MJ, et al., 2003, Gram positive and Gram negative bacteria synergise to cause nitric oxide synthase induction in murine macrophages, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Jimenez R, Warner TD, Belcher PE, et al., 2003, Induction of NOSII and COX activity in primary cultures of murine smooth muscle cells, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188
Warner TD, Mitchell JA, 2003, Nonsteroidal antiinflammatory drugs inhibiting prostanoid efflux: As easy as ABC?, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 9108-9110, ISSN: 0027-8424
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- Citations: 10
Stanford SJ, Walters MJ, Hislop AA, et al., 2003, Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 473, Pages: 135-141, ISSN: 0014-2999
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- Citations: 33
Price S, Mitchell JA, Anning PB, et al., 2003, Type II nitric oxide synthase activity is cardio-protective in experimental sepsis, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 472, Pages: 111-118, ISSN: 0014-2999
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- Citations: 17
Mistry H, Gitlin JM, Mitchell JA, et al., 2003, Endothelium-dependent relaxation and endothelial hyperpolarization by P2Y receptor agonists in rat-isolated mesenteric artery, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 139, Pages: 661-671, ISSN: 0007-1188
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- Citations: 14
Stanford SJ, Walters MJ, Hislop AA, et al., 2003, Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U26-U26, ISSN: 0007-1188
Walters MJ, Warner TD, Bishop-Bailey D, et al., 2003, The PPARγ ligand 15-deoxy-Δ<SUP>12,14</SUP>-prostaglandin J<sub>2</sub> (15D-PGJ<sub>2</sub>) inhibits proliferation and cytokine release from human pulmonary artery smooth muscle, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U66-U66, ISSN: 0007-1188
Stanford SJ, San H, Nabel EG, et al., 2003, Heme oxygenase-1 deficient mice do not appear to have pulmonary hypertension, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U25-U25, ISSN: 0007-1188
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- Citations: 1
Belcher E, Evans TW, Sriskandan S, et al., 2003, Gram-positive <i>Staphylococcus aureus</i> contrasts with Gram-negative <i>Escherichia coli</i> in the induction of tumour necrosis factor-alpha and nitric oxide from macrophages in urine, Meeting of the Intensive-Care-Society, Publisher: OXFORD UNIV PRESS, Pages: 540P-541P, ISSN: 0007-0912
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- Citations: 2
Belcher E, Evans TW, Sriskandan S, et al., 2003, Staphylococcus aureus induces nitric oxide release in cardiovascular tissue via a toll like receptor 2-independent pathway, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U16-U16, ISSN: 0007-1188
Stanford SJ, Hislop AA, Haworth SG, et al., 2003, Induction of heme oxygenase-1 in the porcine lung after birth, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U25-U25, ISSN: 0007-1188
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- Citations: 1
Belcher E, Evans TW, Sriskandan S, et al., 2003, Escherichia coli induces nitric oxide release in cardiovascular tissue via a toll like receptor 4-independent pathway, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U16-U16, ISSN: 0007-1188
Walters MJ, Mitchell JA, 2003, Cigarette smoke extract (CSE) stimulates human THP-1 monocytes directly and synergises with IL-1β to release IL-8, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U22-U22, ISSN: 0007-1188
Patel HJ, Belvisi MG, Bishop-Bailey D, et al., 2003, Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: Relevance for chronic obstructive pulmonary-disease therapy, JOURNAL OF IMMUNOLOGY, Vol: 170, Pages: 2663-2669, ISSN: 0022-1767
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- Citations: 110
Gray PA, Warner TD, Vojnovic I, et al., 2002, Effects of non-steroidal anti-inflammatory drugs on cyclooxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 137, Pages: 1031-1038, ISSN: 0007-1188
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- Citations: 38
Belcher E, Evans TW, Sriskandan S, et al., 2002, The main site of iNOS activity induced by Gram postive <i>Staphylococcus aureus</i> may be blood vessels and not macrophages:: Comparisons with Gram negative <i>Escherichia coli</i>, Winter Meeting of the British-Thoracic-Society, Publisher: BRITISH MED JOURNAL PUBL GROUP, ISSN: 0040-6376
Calatayud S, Warner TD, Breese EJ, et al., 2002, Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis, CYTOKINE, Vol: 20, Pages: 163-167, ISSN: 1043-4666
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- Citations: 19
Warner TD, Mitchell JA, Vane JR, 2002, Cyclo-oxygenase-2 inhibitors and cardiovascular events, LANCET, Vol: 360, Pages: 1700-1701, ISSN: 0140-6736
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- Citations: 5
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