Imperial College London

MrJosephBroomfield

Faculty of EngineeringDepartment of Electrical and Electronic Engineering

Research Postgraduate
 
 
 
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Contact

 

j.broomfield20

 
 
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Location

 

B422Bessemer BuildingSouth Kensington Campus

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Summary

 

Summary

Project summary

Since October 2020, I have been conducting a convergence science PhD funded by Cancer Research UK. My research involves the generation of a prognostic multipanel test for prostate cancer which can be used directly in the clinic. This interdisciplinary work brings together the usage of loop-mediated isothermal amplification (LAMP) and ion-sensitive field-effect transistors (ISFETs) for a rapid and sensitive platform for detection of circulating biomarkers. In particular, the usage of liquid biopsies from the blood, presents the opportunity for a non-invasive prognostic test, overcoming potentially painful procedures present in current testing. 

This work is supervised by Professor Pantelis Georgiou from the Centre for Bio-inspired Technology and Professor Charlotte Bevan from the Department of Surgery and Cancer. 

Previous work



  • MSci in Natural Sciences (Synthetic organic chemistry and molecular and cell biology) with First Class Honours from University College London (UCL). (2016-2020)
  • Master's project conducted with Professor Helen Hailes from UCL, resulting in work published as part of two journal papers. 

Publications

Journals

Roddan R, Subrizi F, Broomfield J, et al., 2021, Chemoenzymatic Cascades toward Methylated Tetrahydroprotoberberine and Protoberberine Alkaloids, Organic Letters, Vol:23, ISSN:1523-7060, Pages:6342-6347

Roddan R, Sula A, Méndez-Sánchez D, et al., 2020, Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases, Communications Chemistry, Vol:3

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