Imperial College London

Dr James A Bull

Faculty of Natural SciencesDepartment of Chemistry

Research Fellow



+44 (0)20 7594 5811j.bull Website




501bMolecular Sciences Research HubWhite City Campus





Dr James A Bull is a Royal Society University Research Fellow in the Department of Chemistry.

Dr Bull’s research focuses on the development of efficient synthetic and catalytic methods to access novel structural motifs and heterocycles of interest in drug discovery.

Group Webpages

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Biographical details

James Bull graduated from the University of Cambridge in 2001 with a First Class Honours MSci degree in Natural Sciences, Chemistry and the Raphael Prize for Organic Chemistry. He then spent a year working at GlaxoSmithKline Stevenage as a Research Scientist in the Medicinal Chemistry Department.

He returned to Cambridge in 2003 to undertake PhD research with Professor Steven V Ley. He completed the total synthesis of bisoxazole antifungal natural product bengazole A and analogues.

In 2007 he joined the group of Professor André B. Charette as a Postdoctoral Fellow at Université de Montréal, Canada. Here he developed an intramolecular Simmons-Smith cyclopropanation reaction.

In 2009 he began independent research at Imperial College London as a Ramsay Memorial Research Fellow (2009-2011), working in the laboratories of Professor Alan Armstrong. From 2011 to 2015 Dr Bull held an EPSRC Career Acceleration Fellowship on "Novel strategies to access chiral heterocycles as potential lead compounds in drug discovery". In January 2016 Dr Bull started a Royal Society University Research Fellowship.

Group News

see: @jamesabull



Higham J, Bull JA, 2020, Transient imine directing groups for the C–H functionalisation of aldehydes, ketones and amines: an update 2018-2020, Organic and Biomolecular Chemistry, ISSN:1477-0520

Green SP, Wheelhouse KM, Payne AD, et al., 2020, On the Use of Differential Scanning Calorimetry for Thermal Hazard Assessment of New Chemistry: Avoiding Explosive Mistakes, Angewandte Chemie International Edition, ISSN:1433-7851

Dubois MAJ, Smith MA, White AJP, et al., 2020, Short Synthesis of Oxetane and Azetidine 3-Aryl-3-carboxylic Acid Derivatives by Selective Furan Oxidative Cleavage, Organic Letters, Vol:22, ISSN:1523-7060, Pages:5279-5283

Coleman JA, Navratna V, Antermite D, et al., 2020, Chemical and structural investigation of the paroxetine-human serotonin transporter complex, Elife, Vol:9, ISSN:2050-084X

Greed S, Briggs E, Idiris F, et al., 2020, Synthesis of highly enantioenriched sulfonimidoyl fluorides and sulfonimidamides by stereospecific SuFEx reaction, Chemistry: a European Journal, ISSN:0947-6539

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